TY - JOUR
T1 - Vulnerable newborn types
T2 - analysis of subnational, population-based birth cohorts for 541 285 live births in 23 countries, 2000–2021
AU - the Subnational Vulnerable Newborn Prevalence Collaborative Group and Vulnerable Newborn Measurement Core Group
AU - Erchick, D. J.
AU - Hazel, E. A.
AU - Katz, J.
AU - Lee, A. C.C.
AU - Diaz, M.
AU - Wu, L. S.F.
AU - Yoshida, S.
AU - Bahl, R.
AU - Grandi, C.
AU - Labrique, A. B.
AU - Rashid, M.
AU - Ahmed, S.
AU - Roy, A. D.
AU - Haque, R.
AU - Shaikh, S.
AU - Baqui, A. H.
AU - Saha, S. K.
AU - Khanam, R.
AU - Rahman, S.
AU - Shapiro, R.
AU - Zash, R.
AU - Silveira, M. F.
AU - Buffarini, R.
AU - Kolsteren, P.
AU - Lachat, C.
AU - Huybregts, L.
AU - Roberfroid, D.
AU - Zeng, L.
AU - Zhu, Z.
AU - He, J.
AU - Qiu, X.
AU - Gebreyesus, S. H.
AU - Tesfamariam, K.
AU - Bekele, D.
AU - Chan, G.
AU - Baye, E.
AU - Workneh, F.
AU - Asante, K. P.
AU - Kaali, E. B.
AU - Adu-Afarwuah, S.
AU - Dewey, K. G.
AU - Gyaase, S.
AU - Wylie, B. J.
AU - Kirkwood, B. R.
AU - Manu, A.
AU - Thulasiraj, R. D.
AU - Tielsch, J.
AU - Chowdhury, R.
AU - Taneja, S.
AU - Babu, G. R.
N1 - Publisher Copyright:
© 2023 The Authors. BJOG: An International Journal of Obstetrics and Gynaecology published by John Wiley & Sons Ltd.
PY - 2025/11
Y1 - 2025/11
N2 - Objective: To examine prevalence of novel newborn types among 541 285 live births in 23 countries from 2000 to 2021. Design: Descriptive multi-country secondary data analysis. Setting: Subnational, population-based birth cohort studies (n = 45) in 23 low- and middle-income countries (LMICs) spanning 2000–2021. Population: Liveborn infants. Methods: Subnational, population-based studies with high-quality birth outcome data from LMICs were invited to join the Vulnerable Newborn Measurement Collaboration. We defined distinct newborn types using gestational age (preterm [PT], term [T]), birthweight for gestational age using INTERGROWTH-21st standards (small for gestational age [SGA], appropriate for gestational age [AGA] or large for gestational age [LGA]), and birthweight (low birthweight, LBW [<2500 g], nonLBW) as ten types (using all three outcomes), six types (by excluding the birthweight categorisation), and four types (by collapsing the AGA and LGA categories). We defined small types as those with at least one classification of LBW, PT or SGA. We presented study characteristics, participant characteristics, data missingness, and prevalence of newborn types by region and study. Results: Among 541 285 live births, 476 939 (88.1%) had non-missing and plausible values for gestational age, birthweight and sex required to construct the newborn types. The median prevalences of ten types across studies were T+AGA+nonLBW (58.0%), T+LGA+nonLBW (3.3%), T+AGA+LBW (0.5%), T+SGA+nonLBW (14.2%), T+SGA+LBW (7.1%), PT+LGA+nonLBW (1.6%), PT+LGA+LBW (0.2%), PT+AGA+nonLBW (3.7%), PT+AGA+LBW (3.6%) and PT+SGA+LBW (1.0%). The median prevalence of small types (six types, 37.6%) varied across studies and within regions and was higher in Southern Asia (52.4%) than in Sub-Saharan Africa (34.9%). Conclusions: Further investigation is needed to describe the mortality risks associated with newborn types and understand the implications of this framework for local targeting of interventions to prevent adverse pregnancy outcomes in LMICs.
AB - Objective: To examine prevalence of novel newborn types among 541 285 live births in 23 countries from 2000 to 2021. Design: Descriptive multi-country secondary data analysis. Setting: Subnational, population-based birth cohort studies (n = 45) in 23 low- and middle-income countries (LMICs) spanning 2000–2021. Population: Liveborn infants. Methods: Subnational, population-based studies with high-quality birth outcome data from LMICs were invited to join the Vulnerable Newborn Measurement Collaboration. We defined distinct newborn types using gestational age (preterm [PT], term [T]), birthweight for gestational age using INTERGROWTH-21st standards (small for gestational age [SGA], appropriate for gestational age [AGA] or large for gestational age [LGA]), and birthweight (low birthweight, LBW [<2500 g], nonLBW) as ten types (using all three outcomes), six types (by excluding the birthweight categorisation), and four types (by collapsing the AGA and LGA categories). We defined small types as those with at least one classification of LBW, PT or SGA. We presented study characteristics, participant characteristics, data missingness, and prevalence of newborn types by region and study. Results: Among 541 285 live births, 476 939 (88.1%) had non-missing and plausible values for gestational age, birthweight and sex required to construct the newborn types. The median prevalences of ten types across studies were T+AGA+nonLBW (58.0%), T+LGA+nonLBW (3.3%), T+AGA+LBW (0.5%), T+SGA+nonLBW (14.2%), T+SGA+LBW (7.1%), PT+LGA+nonLBW (1.6%), PT+LGA+LBW (0.2%), PT+AGA+nonLBW (3.7%), PT+AGA+LBW (3.6%) and PT+SGA+LBW (1.0%). The median prevalence of small types (six types, 37.6%) varied across studies and within regions and was higher in Southern Asia (52.4%) than in Sub-Saharan Africa (34.9%). Conclusions: Further investigation is needed to describe the mortality risks associated with newborn types and understand the implications of this framework for local targeting of interventions to prevent adverse pregnancy outcomes in LMICs.
KW - low birthweight
KW - newborn
KW - preterm birth
KW - small for gestational age
UR - https://www.scopus.com/pages/publications/85158151659
U2 - 10.1111/1471-0528.17510
DO - 10.1111/1471-0528.17510
M3 - 文章
AN - SCOPUS:85158151659
SN - 1470-0328
VL - 132
SP - S20-S36
JO - BJOG: An International Journal of Obstetrics and Gynaecology
JF - BJOG: An International Journal of Obstetrics and Gynaecology
IS - S8
ER -