Visible Light Driven Alkylation of C(sp3)-H Bonds Enabled by 1,6-Hydrogen Atom Transfer/Radical Relay Addition

Zhi Yong Ma; Li Na Guo; Ying You; Fan Yang; Mingyou Hu; Xin Hua Duan

doi:10.1021/acs.orglett.9b01804

Visible Light Driven Alkylation of C(sp³)-H Bonds Enabled by 1,6-Hydrogen Atom Transfer/Radical Relay Addition

Zhi Yong Ma
, Li Na Guo
, Ying You
, Fan Yang
, Mingyou Hu
, Xin Hua Duan

化学学院

Xi'an Jiaotong University
Lanzhou University

科研成果: 期刊稿件 › 文章 › 同行评审

48 引用（Scopus）

摘要

A visible-light-driven sulfamate esters guided alkylation of unactivated C(sp³)-H bonds enabled by a 1,6-HAT/radical addition cascade is described. Not only structurally diverse Michael acceptors but also styrenes are amenable to this alkylation reaction. Notably, the N-H bonds activation radical relay refrained from prefunctionalization and using excess external oxidants.

源语言	英语
页（从-至）	5500-5504
页数	5
期刊	Organic Letters
卷	21
期	14
DOI	https://doi.org/10.1021/acs.orglett.9b01804
出版状态	已出版 - 19 7月 2019

访问文件

10.1021/acs.orglett.9b01804

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{566fccd201da4b48badbf303de080866,

title = "Visible Light Driven Alkylation of C(sp3)-H Bonds Enabled by 1,6-Hydrogen Atom Transfer/Radical Relay Addition",

abstract = "A visible-light-driven sulfamate esters guided alkylation of unactivated C(sp3)-H bonds enabled by a 1,6-HAT/radical addition cascade is described. Not only structurally diverse Michael acceptors but also styrenes are amenable to this alkylation reaction. Notably, the N-H bonds activation radical relay refrained from prefunctionalization and using excess external oxidants.",

author = "Ma, \{Zhi Yong\} and Guo, \{Li Na\} and Ying You and Fan Yang and Mingyou Hu and Duan, \{Xin Hua\}",

note = "Publisher Copyright: {\textcopyright} 2019 American Chemical Society.",

year = "2019",

month = jul,

day = "19",

doi = "10.1021/acs.orglett.9b01804",

language = "英语",

volume = "21",

pages = "5500--5504",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "14",

}

TY - JOUR

T1 - Visible Light Driven Alkylation of C(sp3)-H Bonds Enabled by 1,6-Hydrogen Atom Transfer/Radical Relay Addition

AU - Ma, Zhi Yong

AU - Guo, Li Na

AU - You, Ying

AU - Yang, Fan

AU - Hu, Mingyou

AU - Duan, Xin Hua

PY - 2019/7/19

Y1 - 2019/7/19

N2 - A visible-light-driven sulfamate esters guided alkylation of unactivated C(sp3)-H bonds enabled by a 1,6-HAT/radical addition cascade is described. Not only structurally diverse Michael acceptors but also styrenes are amenable to this alkylation reaction. Notably, the N-H bonds activation radical relay refrained from prefunctionalization and using excess external oxidants.

AB - A visible-light-driven sulfamate esters guided alkylation of unactivated C(sp3)-H bonds enabled by a 1,6-HAT/radical addition cascade is described. Not only structurally diverse Michael acceptors but also styrenes are amenable to this alkylation reaction. Notably, the N-H bonds activation radical relay refrained from prefunctionalization and using excess external oxidants.

UR - https://www.scopus.com/pages/publications/85068328712

U2 - 10.1021/acs.orglett.9b01804

DO - 10.1021/acs.orglett.9b01804

M3 - 文章

C2 - 31246029

AN - SCOPUS:85068328712

SN - 1523-7060

VL - 21

SP - 5500

EP - 5504

JO - Organic Letters

JF - Organic Letters

IS - 14

ER -

Visible Light Driven Alkylation of C(sp3)-H Bonds Enabled by 1,6-Hydrogen Atom Transfer/Radical Relay Addition

摘要

访问文件

其它文件与链接

学术指纹

引用此

Visible Light Driven Alkylation of C(sp³)-H Bonds Enabled by 1,6-Hydrogen Atom Transfer/Radical Relay Addition