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Ultrasound-enhanced extravasation of multifunctional nanodroplets from leaky vessel

  • Y. J. Zong
  • , Xinru Zou
  • , Rongrong Wang
  • , Yi Feng
  • , Mingxi Wan
  • Xi'an Jiaotong University

科研成果: 书/报告/会议事项章节会议稿件同行评审

2 引用 (Scopus)

摘要

Poorly organized vascular architecture of tumor tissue allows extravasation of drug-loaded nanoparticles through the large interendothelial gaps. Extravasated perfluorocarbon nanodroplets can convert into microbubbles under ultrasound irradiation to imaging or deliver drug for tumor treatment. However an increased interstitial fluid pressure in tumor tissue hinders convectional transport of drug carriers across blood vessel walls, thus extravasation of sufficient amounts of droplets remains a major challenge. In this paper, we propose an ultrasound-enhanced extravasation strategy using synergetic effect of acoustic radiation force and cavitation enhanced penetration.

源语言英语
主期刊名2015 IEEE International Ultrasonics Symposium, IUS 2015
出版商Institute of Electrical and Electronics Engineers Inc.
ISBN(电子版)9781479981823
DOI
出版状态已出版 - 13 11月 2015
活动IEEE International Ultrasonics Symposium, IUS 2015 - Taipei, 中国台湾
期限: 21 10月 201524 10月 2015

丛书

姓名2015 IEEE International Ultrasonics Symposium, IUS 2015

会议

会议IEEE International Ultrasonics Symposium, IUS 2015
国家/地区中国台湾
Taipei
时期21/10/1524/10/15

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