TY - JOUR
T1 - The viral, epidemiologic, clinical characteristics and potential therapy options for COVID-19
T2 - A review
AU - Li, C.
AU - Xu, B. H.
N1 - Publisher Copyright:
© 2020 Verduci Editore s.r.l. All rights reserved.
PY - 2020
Y1 - 2020
N2 - Coronavirus Disease-2019 (COVID-19) caused by SARS-CoV-2 infection has rapidly spread all over the world, in just two months. As of 27 March, globally, 509,164 cases confirmed included 23,335 deaths in approximately 150 countries. Recently, WHO has defined COVID-19 as a global pandemic, and considerable researches have focused on the identification and prevention of SARS-CoV-2. As a result, accumulated publications successively reported their early findings, leading to the constant updating of information, which might make confusion for readers. Therefore, this review summarized the current researches about the genomic evolution, variation of SARS-CoV-2, and demonstrated its viral structure for pathogenesis. Meanwhile, we analyzed the epidemiologic and clinical characteristics of COVID-19, in order to provide recommendations for present clinical treatments and inspirations for potential therapy options.
AB - Coronavirus Disease-2019 (COVID-19) caused by SARS-CoV-2 infection has rapidly spread all over the world, in just two months. As of 27 March, globally, 509,164 cases confirmed included 23,335 deaths in approximately 150 countries. Recently, WHO has defined COVID-19 as a global pandemic, and considerable researches have focused on the identification and prevention of SARS-CoV-2. As a result, accumulated publications successively reported their early findings, leading to the constant updating of information, which might make confusion for readers. Therefore, this review summarized the current researches about the genomic evolution, variation of SARS-CoV-2, and demonstrated its viral structure for pathogenesis. Meanwhile, we analyzed the epidemiologic and clinical characteristics of COVID-19, in order to provide recommendations for present clinical treatments and inspirations for potential therapy options.
KW - Clinical characteristics
KW - COVID-19
KW - Epidemiology
KW - Genomic structure
KW - Pathogenesis
KW - SARS-CoV-2
KW - Therapy options
UR - https://www.scopus.com/pages/publications/85084379496
U2 - 10.26355/eurrev_202004_21044
DO - 10.26355/eurrev_202004_21044
M3 - 文献综述
C2 - 32373998
AN - SCOPUS:85084379496
SN - 1128-3602
VL - 24
SP - 4576
EP - 4584
JO - European Review for Medical and Pharmacological Sciences
JF - European Review for Medical and Pharmacological Sciences
IS - 8
ER -