Temperature-uniformity study on transverse flux induction heating applied to rapid PCR

Induction heating has been widely used in industrial and domestic fields due to its rapid heating rate, low power, no pollution and easy control. However, its temperature uniformity isn't good enough to meet the requirements of precise temperature control. The application in the field of nucleic acid amplification instruments (PCR instruments) is basically blank. In response to this situation, a method is provided to improve the temperature uniformity of transverse flux induction heating, which, for the first time, is applied to the study on rapid PCR. The principle of electromagnetic induction heating is analysed, a specific method for calculating the basic parameters of the transverse flux induction coil is introduced, then, different coil structures are designed and analysed by COMSOL Multiphysics according to the determined parameters, simulation analysis and comparison are carried out to obtain an optimal coil structure. The results show that, with other parameters unchanged, the temperature uniformity of the entire heating plane can be up to ±0.5 °C by adjusting the coil structure, which can meet the requirements of precise temperature control, and have a revolutionary impact on the study of rapid PCR.