Serum levels of uric acid may have a potential role in the management of immediate delivery or prolongation of pregnancy in severe preeclampsia

Dan Liu; Chunfang Li; Pu Huang; Jing Fu; Xin Dong; Yunhui Tang; Xuelan Li; Qi Chen

doi:10.1080/10641955.2020.1761377

Serum levels of uric acid may have a potential role in the management of immediate delivery or prolongation of pregnancy in severe preeclampsia

Dan Liu
, Chunfang Li
, Pu Huang
, Jing Fu
, Xin Dong
, Yunhui Tang
, Xuelan Li
, Qi Chen

The First Affiliated Hospital of Xi’an Jiaotong University
Fudan University
The University of Auckland

科研成果: 期刊稿件 › 文章 › 同行评审

8 引用（Scopus）

摘要

Objective: To investigate the biomarker(s) that could affect the decision for immediate or delayed delivery in severe preeclampsia. Methods: Data on serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatinine, blood urea nitrogen (BUN), uric acid (UA) and platelet counts from 134 cases were collected and analysed. Results: Higher UA levels were seen in case with immediate delivery. Higher stillbirth was seen in cases with delayed delivery. Conclusion: UA levels could be a potential management biomarker for immediate or delayed delivery in severe preeclampsia. However, the higher risk of stillbirth must be considered in delayed delivery.

源语言	英语
页（从-至）	260-266
页数	7
期刊	Hypertension in Pregnancy
卷	39
期	3
DOI	https://doi.org/10.1080/10641955.2020.1761377
出版状态	已出版 - 2 7月 2020
已对外发布	是

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title = "Serum levels of uric acid may have a potential role in the management of immediate delivery or prolongation of pregnancy in severe preeclampsia",

abstract = "Objective: To investigate the biomarker(s) that could affect the decision for immediate or delayed delivery in severe preeclampsia. Methods: Data on serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatinine, blood urea nitrogen (BUN), uric acid (UA) and platelet counts from 134 cases were collected and analysed. Results: Higher UA levels were seen in case with immediate delivery. Higher stillbirth was seen in cases with delayed delivery. Conclusion: UA levels could be a potential management biomarker for immediate or delayed delivery in severe preeclampsia. However, the higher risk of stillbirth must be considered in delayed delivery.",

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author = "Dan Liu and Chunfang Li and Pu Huang and Jing Fu and Xin Dong and Yunhui Tang and Xuelan Li and Qi Chen",

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doi = "10.1080/10641955.2020.1761377",

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T1 - Serum levels of uric acid may have a potential role in the management of immediate delivery or prolongation of pregnancy in severe preeclampsia

AU - Liu, Dan

AU - Li, Chunfang

AU - Huang, Pu

AU - Fu, Jing

AU - Dong, Xin

AU - Tang, Yunhui

AU - Li, Xuelan

AU - Chen, Qi

PY - 2020/7/2

Y1 - 2020/7/2

N2 - Objective: To investigate the biomarker(s) that could affect the decision for immediate or delayed delivery in severe preeclampsia. Methods: Data on serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatinine, blood urea nitrogen (BUN), uric acid (UA) and platelet counts from 134 cases were collected and analysed. Results: Higher UA levels were seen in case with immediate delivery. Higher stillbirth was seen in cases with delayed delivery. Conclusion: UA levels could be a potential management biomarker for immediate or delayed delivery in severe preeclampsia. However, the higher risk of stillbirth must be considered in delayed delivery.

AB - Objective: To investigate the biomarker(s) that could affect the decision for immediate or delayed delivery in severe preeclampsia. Methods: Data on serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatinine, blood urea nitrogen (BUN), uric acid (UA) and platelet counts from 134 cases were collected and analysed. Results: Higher UA levels were seen in case with immediate delivery. Higher stillbirth was seen in cases with delayed delivery. Conclusion: UA levels could be a potential management biomarker for immediate or delayed delivery in severe preeclampsia. However, the higher risk of stillbirth must be considered in delayed delivery.

KW - Severe preeclampsia

KW - immediate delivery

KW - prolongation

KW - renal function

KW - uric acid

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DO - 10.1080/10641955.2020.1761377

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AN - SCOPUS:85084264489

SN - 1064-1955

VL - 39

SP - 260

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JO - Hypertension in Pregnancy

JF - Hypertension in Pregnancy

IS - 3

ER -

Serum levels of uric acid may have a potential role in the management of immediate delivery or prolongation of pregnancy in severe preeclampsia

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