TY - JOUR
T1 - Review on estimation of postmortem interval using FTIR spectroscopy
AU - Huang, Ping
AU - Tuo, Ya
AU - Wang, Zhen Yuan
PY - 2010/6/25
Y1 - 2010/6/25
N2 - Estimation of the postmortem interval (PMI) is a practical task in daily forensic casework. Researches on PMI is an important practical project in forensic field. Estimation of the time since death is influenced by internal and external, antemortem and postmortem factors, thus the old methods have limitations. Fourier transform infrared (FTIR) spectroscopy has been applied to study the pure protein, nucleic acid and carbohydrate and to detect the changes in complex cells and tissues. At present because the powerful software has could be used to achieve the spectrum transformation, smoothing, baseline correction and normalization, it is possible to analyze the samples quantitatively with the FTIR which has been applied in the biology and clinical medicine. This paper has reviewed the mechanism of FTIR and its application in biomedicine. The postmortem FTIR spectral changes were also discussed, which showed its potential for estimating PMI.
AB - Estimation of the postmortem interval (PMI) is a practical task in daily forensic casework. Researches on PMI is an important practical project in forensic field. Estimation of the time since death is influenced by internal and external, antemortem and postmortem factors, thus the old methods have limitations. Fourier transform infrared (FTIR) spectroscopy has been applied to study the pure protein, nucleic acid and carbohydrate and to detect the changes in complex cells and tissues. At present because the powerful software has could be used to achieve the spectrum transformation, smoothing, baseline correction and normalization, it is possible to analyze the samples quantitatively with the FTIR which has been applied in the biology and clinical medicine. This paper has reviewed the mechanism of FTIR and its application in biomedicine. The postmortem FTIR spectral changes were also discussed, which showed its potential for estimating PMI.
KW - Forensic pathology
KW - Postmortem interval estimation
KW - Review[publication type]
KW - Spectroscopy, Fourier transform infrared
UR - https://www.scopus.com/pages/publications/77956300280
U2 - 10.3969/j.issn.1004-5619.2010.03.011
DO - 10.3969/j.issn.1004-5619.2010.03.011
M3 - 文章
C2 - 20707280
AN - SCOPUS:77956300280
SN - 1004-5619
VL - 26
SP - 198
EP - 201
JO - Journal of Forensic Medicine
JF - Journal of Forensic Medicine
IS - 3
ER -