Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus

Haitao Zhu; Xiaoge Zhang; Yayi He; Liang Yu; Yi Lü; Kaili Pan; Bo Wang; Guoqiang Chen

doi:10.7507/1002-1892.201707049

Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus

Haitao Zhu
, Xiaoge Zhang
, Yayi He
, Liang Yu
, Yi Lü
, Kaili Pan
, Bo Wang
, Guoqiang Chen

医学部

Xi'an Jiaotong University
Northwest Women’s and Children’s Hospital

科研成果: 期刊稿件 › 文献综述 › 同行评审

1 引用（Scopus）

摘要

目的: 综述糖尿病胰岛替代治疗的供体细胞来源及选择的研究进展。.

方法: 查阅近年来国内外关于糖尿病胰岛替代治疗及供体细胞来源的相关文献，进行总结分析。.

结果: 供体来源短缺仍是胰岛移植（pancreatic islet transplantation，PIT）面临的主要难题。目前，除同种异体/自体供胰外，异种（猪）胰岛、干细胞诱导胰岛及胰岛细胞株制备和应用等方面也取得了重要进展，潜在扩大了可植入细胞来源。.

结论: 充足、合适的供体细胞来源是临床广泛开展 PIT 治疗 1 型糖尿病（type 1 diabetes mellitus，T1DM）的前提。社会捐赠体系的完善，免疫耐受诱导、基因与生物工程等技术的发展有望解决供体细胞短缺问题，并为临床细胞替代治疗 T1DM 奠定了基础。.

源语言	英语
页（从-至）	104-111
页数	8
期刊	Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
卷	32
期	1
DOI	https://doi.org/10.7507/1002-1892.201707049
出版状态	已出版 - 1 1月 2018

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

可持续发展目标 3 良好健康与福祉

访问文件

10.7507/1002-1892.201707049

其它文件与链接

链接到 Scopus 的出版物

引用此

Zhu, H., Zhang, X., He, Y., Yu, L., Lü, Y., Pan, K., Wang, B., & Chen, G. (2018). Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 32(1), 104-111. https://doi.org/10.7507/1002-1892.201707049

@article{37694dbb73044104bfc03863cd4b23c3,

title = "Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus",

abstract = "目的: 综述糖尿病胰岛替代治疗的供体细胞来源及选择的研究进展。.方法: 查阅近年来国内外关于糖尿病胰岛替代治疗及供体细胞来源的相关文献，进行总结分析。.结果: 供体来源短缺仍是胰岛移植（pancreatic islet transplantation，PIT）面临的主要难题。目前，除同种异体/自体供胰外，异种（猪）胰岛、干细胞诱导胰岛及胰岛细胞株制备和应用等方面也取得了重要进展，潜在扩大了可植入细胞来源。.结论: 充足、合适的供体细胞来源是临床广泛开展 PIT 治疗 1 型糖尿病（type 1 diabetes mellitus，T1DM）的前提。社会捐赠体系的完善，免疫耐受诱导、基因与生物工程等技术的发展有望解决供体细胞短缺问题，并为临床细胞替代治疗 T1DM 奠定了基础。.",

keywords = "Islet transplantation, donator, stem cells, type 1 diabetes mellitus, xenotransplantation",

author = "Haitao Zhu and Xiaoge Zhang and Yayi He and Liang Yu and Yi L{\"u} and Kaili Pan and Bo Wang and Guoqiang Chen",

year = "2018",

month = jan,

day = "1",

doi = "10.7507/1002-1892.201707049",

language = "英语",

volume = "32",

pages = "104--111",

journal = "Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery",

issn = "1002-1892",

publisher = "West China University of Medical Science",

number = "1",

}

Zhu, H, Zhang, X, He, Y, Yu, L, Lü, Y, Pan, K, Wang, B & Chen, G 2018, 'Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus', Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 卷 32, 号码 1, 页码 104-111. https://doi.org/10.7507/1002-1892.201707049

Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus. / Zhu, Haitao; Zhang, Xiaoge; He, Yayi 等.
在: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 卷 32, 号码 1, 01.01.2018, 页码 104-111.

科研成果: 期刊稿件 › 文献综述 › 同行评审

TY - JOUR

T1 - Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus

AU - Zhu, Haitao

AU - Zhang, Xiaoge

AU - He, Yayi

AU - Yu, Liang

AU - Lü, Yi

AU - Pan, Kaili

AU - Wang, Bo

AU - Chen, Guoqiang

PY - 2018/1/1

Y1 - 2018/1/1

N2 - 目的: 综述糖尿病胰岛替代治疗的供体细胞来源及选择的研究进展。.方法: 查阅近年来国内外关于糖尿病胰岛替代治疗及供体细胞来源的相关文献，进行总结分析。.结果: 供体来源短缺仍是胰岛移植（pancreatic islet transplantation，PIT）面临的主要难题。目前，除同种异体/自体供胰外，异种（猪）胰岛、干细胞诱导胰岛及胰岛细胞株制备和应用等方面也取得了重要进展，潜在扩大了可植入细胞来源。.结论: 充足、合适的供体细胞来源是临床广泛开展 PIT 治疗 1 型糖尿病（type 1 diabetes mellitus，T1DM）的前提。社会捐赠体系的完善，免疫耐受诱导、基因与生物工程等技术的发展有望解决供体细胞短缺问题，并为临床细胞替代治疗 T1DM 奠定了基础。.

AB - 目的: 综述糖尿病胰岛替代治疗的供体细胞来源及选择的研究进展。.方法: 查阅近年来国内外关于糖尿病胰岛替代治疗及供体细胞来源的相关文献，进行总结分析。.结果: 供体来源短缺仍是胰岛移植（pancreatic islet transplantation，PIT）面临的主要难题。目前，除同种异体/自体供胰外，异种（猪）胰岛、干细胞诱导胰岛及胰岛细胞株制备和应用等方面也取得了重要进展，潜在扩大了可植入细胞来源。.结论: 充足、合适的供体细胞来源是临床广泛开展 PIT 治疗 1 型糖尿病（type 1 diabetes mellitus，T1DM）的前提。社会捐赠体系的完善，免疫耐受诱导、基因与生物工程等技术的发展有望解决供体细胞短缺问题，并为临床细胞替代治疗 T1DM 奠定了基础。.

KW - Islet transplantation

KW - donator

KW - stem cells

KW - type 1 diabetes mellitus

KW - xenotransplantation

UR - https://www.scopus.com/pages/publications/85054438811

U2 - 10.7507/1002-1892.201707049

DO - 10.7507/1002-1892.201707049

M3 - 文献综述

C2 - 29806374

AN - SCOPUS:85054438811

SN - 1002-1892

VL - 32

SP - 104

EP - 111

JO - Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery

JF - Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery

IS - 1

ER -

Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus

摘要

联合国可持续发展目标

访问文件

其它文件与链接

学术指纹

引用此