TY - JOUR
T1 - Research progress on pharmacological activities and clinical applications of Guizhi Fuling Capsule
AU - Zhong, Yun Xi
AU - Sun, Jian Guo
AU - Wang, Guang Ji
N1 - Publisher Copyright:
© 2016, Editorial Office of Chinese Traditional and Herbal Drugs. All right reserved.
PY - 2016/9/12
Y1 - 2016/9/12
N2 - Guizhi Fuling Capsule (GZFL), composed of Cassia Twig, Pachyma Cocos, Cortex Moutan, Radices Paeoniae Alba, and Peach Kernel, is a compound Chinese medicine preparation refined by modern technology. Modern pharmacology study shows that GZFL has pharmacological activities such as anti-inflammatory, analgesic, antitumor, smooth muscle relaxing, endocrine adjusting, and immunity enhancing activities. GZFL can be used in treatment of gynecological disease such as uterine fibroids, pelvic inflammatory disease, dysmenorrheal, and endometriosis in clinic, and it can be also used for the treatment of varicocele, hyperplasia of prostate, stroke, and carotid atherosclerosis. The phase II clinical trials of GZFL in treatment of primary dysmenorrhea in the United States of America have already finished. This paper makes a systematic review of the pharmacological activities and clinical applications of GZFL in recent years, in order to provide reference for its further development and utilization.
AB - Guizhi Fuling Capsule (GZFL), composed of Cassia Twig, Pachyma Cocos, Cortex Moutan, Radices Paeoniae Alba, and Peach Kernel, is a compound Chinese medicine preparation refined by modern technology. Modern pharmacology study shows that GZFL has pharmacological activities such as anti-inflammatory, analgesic, antitumor, smooth muscle relaxing, endocrine adjusting, and immunity enhancing activities. GZFL can be used in treatment of gynecological disease such as uterine fibroids, pelvic inflammatory disease, dysmenorrheal, and endometriosis in clinic, and it can be also used for the treatment of varicocele, hyperplasia of prostate, stroke, and carotid atherosclerosis. The phase II clinical trials of GZFL in treatment of primary dysmenorrhea in the United States of America have already finished. This paper makes a systematic review of the pharmacological activities and clinical applications of GZFL in recent years, in order to provide reference for its further development and utilization.
KW - Analgesic activity
KW - Anti-inflammatory activity
KW - Antitumor activity
KW - Cassia Twig
KW - Compound Chinese medicine preparation
KW - Cortex Moutan
KW - Guizhi Fuling Capsule
KW - Pachyma Cocos
KW - Peach Kernel
KW - Primary dysmenorrheal
KW - Radices Paeoniae Alba
KW - Varicocele
UR - https://www.scopus.com/pages/publications/84995377805
U2 - 10.7501/j.issn.0253-2670.2016.17.026
DO - 10.7501/j.issn.0253-2670.2016.17.026
M3 - 文献综述
AN - SCOPUS:84995377805
SN - 0253-2670
VL - 47
SP - 3115
EP - 3120
JO - Chinese Traditional and Herbal Drugs
JF - Chinese Traditional and Herbal Drugs
IS - 17
ER -