Regioselective S' Mitsunobu reaction of Morita-Baylis-Hillman alcohols: A facile and stereoselective synthesis of α-alkylidene-ß-hydrazino acid derivatives

Silong Xu; Jian Shang; Junjie Zhang; Yuhai Tang

doi:10.3762/bjoc.10.98

Regioselective S' Mitsunobu reaction of Morita-Baylis-Hillman alcohols: A facile and stereoselective synthesis of α-alkylidene-ß-hydrazino acid derivatives

Silong Xu
, Jian Shang
, Junjie Zhang
, Yuhai Tang

化学学院

Xi'an Jiaotong University

科研成果: 期刊稿件 › 文章 › 同行评审

6 引用（Scopus）

摘要

A highly regioselective S' Mitsunobu reaction between Morita-Baylis-Hillman (MBH) alcohols, azodicarboxylates, and triphenylphosphine is developed, which provides an easy access to a-alkylidene-ß-hydrazino acid derivatives in high yields and good stereoselectivity. This reaction represents the first direct transformation of MBH alcohols into hydrazines.

源语言	英语
页（从-至）	990-995
页数	6
期刊	Beilstein Journal of Organic Chemistry
卷	10
DOI	https://doi.org/10.3762/bjoc.10.98
出版状态	已出版 - 30 4月 2014

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title = "Regioselective S' Mitsunobu reaction of Morita-Baylis-Hillman alcohols: A facile and stereoselective synthesis of α-alkylidene-{\ss}-hydrazino acid derivatives",

abstract = "A highly regioselective S' Mitsunobu reaction between Morita-Baylis-Hillman (MBH) alcohols, azodicarboxylates, and triphenylphosphine is developed, which provides an easy access to a-alkylidene-{\ss}-hydrazino acid derivatives in high yields and good stereoselectivity. This reaction represents the first direct transformation of MBH alcohols into hydrazines.",

keywords = "Azodicarboxylate, Hydrazine, Mitsunobu reaction, Morita-baylis-hillman, S' reaction",

author = "Silong Xu and Jian Shang and Junjie Zhang and Yuhai Tang",

year = "2014",

month = apr,

day = "30",

doi = "10.3762/bjoc.10.98",

language = "英语",

volume = "10",

pages = "990--995",

journal = "Beilstein Journal of Organic Chemistry",

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TY - JOUR

T1 - Regioselective S' Mitsunobu reaction of Morita-Baylis-Hillman alcohols

T2 - A facile and stereoselective synthesis of α-alkylidene-ß-hydrazino acid derivatives

AU - Xu, Silong

AU - Shang, Jian

AU - Zhang, Junjie

AU - Tang, Yuhai

PY - 2014/4/30

Y1 - 2014/4/30

N2 - A highly regioselective S' Mitsunobu reaction between Morita-Baylis-Hillman (MBH) alcohols, azodicarboxylates, and triphenylphosphine is developed, which provides an easy access to a-alkylidene-ß-hydrazino acid derivatives in high yields and good stereoselectivity. This reaction represents the first direct transformation of MBH alcohols into hydrazines.

AB - A highly regioselective S' Mitsunobu reaction between Morita-Baylis-Hillman (MBH) alcohols, azodicarboxylates, and triphenylphosphine is developed, which provides an easy access to a-alkylidene-ß-hydrazino acid derivatives in high yields and good stereoselectivity. This reaction represents the first direct transformation of MBH alcohols into hydrazines.

KW - Azodicarboxylate

KW - Hydrazine

KW - Mitsunobu reaction

KW - Morita-baylis-hillman

KW - S' reaction

UR - https://www.scopus.com/pages/publications/84899845060

U2 - 10.3762/bjoc.10.98

DO - 10.3762/bjoc.10.98

M3 - 文章

AN - SCOPUS:84899845060

SN - 1860-5397

VL - 10

SP - 990

EP - 995

JO - Beilstein Journal of Organic Chemistry

JF - Beilstein Journal of Organic Chemistry

ER -

Regioselective S' Mitsunobu reaction of Morita-Baylis-Hillman alcohols: A facile and stereoselective synthesis of α-alkylidene-ß-hydrazino acid derivatives

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