Red/NIR-emissive AIE nanoprobe to track subcellular dynamics in a photodynamic therapy process

Yu Zhou; Yalei Jiang; Lanqiong Zhang; Yukang Li; Ying Hao; Pei Zhou; Zhi Wang; Youming Zhang; Jen Shyang Ni; Yanzi Xu; Lingjie Meng; Dongfeng Dang

doi:10.1039/d5cc04640h

Red/NIR-emissive AIE nanoprobe to track subcellular dynamics in a photodynamic therapy process

Yu Zhou
, Yalei Jiang
, Lanqiong Zhang
, Yukang Li
, Ying Hao
, Pei Zhou
, Zhi Wang
, Youming Zhang
, Jen Shyang Ni
, Yanzi Xu
, Lingjie Meng
, Dongfeng Dang

化学学院

Xi'an Jiaotong University
The First Affiliated Hospital of Xi’an Jiaotong University
Shenzhen Institute of Information Technology
National Kaohsiung University of Science and Technology

科研成果: 期刊稿件 › 文章 › 同行评审

1 引用（Scopus）

摘要

Precise monitoring of cancer treatment at the subcellular level remains a critical challenge. Therefore, a lysosome-specific AIE nanoprobe integrating stimulated emission depletion (STED) imaging and photodynamic therapy is reported here. The probe enables real-time visualization of lysosomal dynamics and reactive oxygen species (ROS)-mediated apoptosis, offering a powerful platform for high-resolution imaging-guided cancer diagnosis and treatment.

源语言	英语
页（从-至）	568-571
页数	4
期刊	Chemical Communications
卷	62
期	2
DOI	https://doi.org/10.1039/d5cc04640h
出版状态	已出版 - 8 1月 2026

联合国可持续发展目标

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可持续发展目标 3 良好健康与福祉

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10.1039/d5cc04640h

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title = "Red/NIR-emissive AIE nanoprobe to track subcellular dynamics in a photodynamic therapy process",

abstract = "Precise monitoring of cancer treatment at the subcellular level remains a critical challenge. Therefore, a lysosome-specific AIE nanoprobe integrating stimulated emission depletion (STED) imaging and photodynamic therapy is reported here. The probe enables real-time visualization of lysosomal dynamics and reactive oxygen species (ROS)-mediated apoptosis, offering a powerful platform for high-resolution imaging-guided cancer diagnosis and treatment.",

author = "Yu Zhou and Yalei Jiang and Lanqiong Zhang and Yukang Li and Ying Hao and Pei Zhou and Zhi Wang and Youming Zhang and Ni, \{Jen Shyang\} and Yanzi Xu and Lingjie Meng and Dongfeng Dang",

note = "Publisher Copyright: This journal is {\textcopyright} The Royal Society of Chemistry, 2026",

year = "2026",

month = jan,

day = "8",

doi = "10.1039/d5cc04640h",

language = "英语",

volume = "62",

pages = "568--571",

journal = "Chemical Communications",

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TY - JOUR

T1 - Red/NIR-emissive AIE nanoprobe to track subcellular dynamics in a photodynamic therapy process

AU - Zhou, Yu

AU - Jiang, Yalei

AU - Zhang, Lanqiong

AU - Li, Yukang

AU - Hao, Ying

AU - Zhou, Pei

AU - Wang, Zhi

AU - Zhang, Youming

AU - Ni, Jen Shyang

AU - Xu, Yanzi

AU - Meng, Lingjie

AU - Dang, Dongfeng

PY - 2026/1/8

Y1 - 2026/1/8

N2 - Precise monitoring of cancer treatment at the subcellular level remains a critical challenge. Therefore, a lysosome-specific AIE nanoprobe integrating stimulated emission depletion (STED) imaging and photodynamic therapy is reported here. The probe enables real-time visualization of lysosomal dynamics and reactive oxygen species (ROS)-mediated apoptosis, offering a powerful platform for high-resolution imaging-guided cancer diagnosis and treatment.

AB - Precise monitoring of cancer treatment at the subcellular level remains a critical challenge. Therefore, a lysosome-specific AIE nanoprobe integrating stimulated emission depletion (STED) imaging and photodynamic therapy is reported here. The probe enables real-time visualization of lysosomal dynamics and reactive oxygen species (ROS)-mediated apoptosis, offering a powerful platform for high-resolution imaging-guided cancer diagnosis and treatment.

UR - https://www.scopus.com/pages/publications/105023849506

U2 - 10.1039/d5cc04640h

DO - 10.1039/d5cc04640h

M3 - 文章

C2 - 41347587

AN - SCOPUS:105023849506

SN - 1359-7345

VL - 62

SP - 568

EP - 571

JO - Chemical Communications

JF - Chemical Communications

IS - 2

ER -

Red/NIR-emissive AIE nanoprobe to track subcellular dynamics in a photodynamic therapy process

摘要

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