TY - JOUR
T1 - Recent advances in cell membrane chromatography for traditional Chinese medicines analysis
AU - Hou, Xiaofang
AU - Wang, Sicen
AU - Zhang, Tao
AU - Ma, Jing
AU - Zhang, Jie
AU - Zhang, Yanmin
AU - Lu, Wen
AU - He, Huaizhen
AU - He, Langchong
N1 - Publisher Copyright:
© 2014 Elsevier B.V.
PY - 2014/4/1
Y1 - 2014/4/1
N2 - Traditional Chinese medicines (TCMs) have been used for preventative care for thousands of years. The active components are the basis for the pharmacodynamics of TCMs, and they can be an important source of lead compounds. As a bioaffinity chromatography technique, cell membrane chromatography (CMC) has been developed for almost 20 years since 1996. It has been proven to be a useful method for studying drug-receptor interactions and screening active components from medicinal herbs. In our review in 2007 (Drug Discov. Ther., 1 (2007) 104-107), the preparation, identification, evaluation, and preliminary applications of CMC stationary phases were presented. In this article, we briefly review some of the latest progress and applications about CMC including instrument development, research on drug-receptor interactions, screening active components from TCMs, and quality control of TCMs.
AB - Traditional Chinese medicines (TCMs) have been used for preventative care for thousands of years. The active components are the basis for the pharmacodynamics of TCMs, and they can be an important source of lead compounds. As a bioaffinity chromatography technique, cell membrane chromatography (CMC) has been developed for almost 20 years since 1996. It has been proven to be a useful method for studying drug-receptor interactions and screening active components from medicinal herbs. In our review in 2007 (Drug Discov. Ther., 1 (2007) 104-107), the preparation, identification, evaluation, and preliminary applications of CMC stationary phases were presented. In this article, we briefly review some of the latest progress and applications about CMC including instrument development, research on drug-receptor interactions, screening active components from TCMs, and quality control of TCMs.
KW - Active components
KW - Cell membrane chromatography
KW - Drug-receptor interactions
KW - Quality control
KW - Traditional Chinese medicines
UR - https://www.scopus.com/pages/publications/84908328975
U2 - 10.1016/j.jpba.2014.05.021
DO - 10.1016/j.jpba.2014.05.021
M3 - 文章
C2 - 24972757
AN - SCOPUS:84908328975
SN - 0731-7085
VL - 101
SP - 141
EP - 150
JO - Journal of Pharmaceutical and Biomedical Analysis
JF - Journal of Pharmaceutical and Biomedical Analysis
ER -