Protective effect of neuronavigation microsurgery on brain function and its accuracy in the treatment of intracranial minute occupying-space lesions

Aim: To study protective effects of the microsurgery on intracranial minute occupying space lesions under the direction of the neuronavigation system and its accuracy. Methods: StealthStation neuronavigation system was used to direct the microsurgical incision for 26 cases with intracranial minute occupying space lesions and fiducial accuracy, intraoperative accuracy, intraoperative brain shift, operative effect and complications were analyzed. Results: Mean fiducial error (MFE) and predicted accuracy at 10 cm (PA) were (2.6 ± 0.9) rmn and (2.5 ± 0.8) nim, respectively. Sustained accuracy including SA1 (k-wire), SA2 (after craniotomy), SA3 (after lesion removal) were (2.4 ± 0.8) mm, (1.3 ± 0.8) mm and(1.5 ± 1.0) mm, respectively. SA2 and SA3 to monitor intraoperative accuracy had no obvious difference (t = 0.353, P > 0.05). Intraoperative brain shift was (1.5 ± 0.4) mm. The rate of total resection was 100%. Clinical manifestation was improved in 21 cases and unchanged in 5 cases after operation, and there were no operative complications and death. Conclusion: The neuronavigation system to direct the microsurgery for intracranial minute occupying space lesion has the high accuracy for location and operation, but has minimal invasion for cerebral tissue. It is helpful for seeking and totally resecting lesions, protecting brain functional region and decreasing the incidence of operative complications.