Progress of Selenium Deficiency in the Pathogenesis of Arthropathies and Selenium Supplement for Their Treatment

Huan Deng; Haobiao Liu; Zhihao Yang; Miaoye Bao; Xue Lin; Jing Han; Chengjuan Qu

doi:10.1007/s12011-021-03022-4

Progress of Selenium Deficiency in the Pathogenesis of Arthropathies and Selenium Supplement for Their Treatment

Huan Deng
, Haobiao Liu
, Zhihao Yang
, Miaoye Bao
, Xue Lin
, Jing Han
, Chengjuan Qu

医学部

Xi'an Jiaotong University
Umeå University

科研成果: 期刊稿件 › 文献综述 › 同行评审

45 引用（Scopus）

摘要

Selenium, an essential trace element for human health, exerts an indispensable effect in maintaining physiological homeostasis and functions in the body. Selenium deficiency is associated with arthropathies, such as Kashin-Beck disease, rheumatoid arthritis, osteoarthritis, and osteoporosis. Selenium deficiency mainly affects the normal physiological state of bone and cartilage through oxidative stress reaction and immune reaction. This review aims to explore the role of selenium deficiency and its mechanisms existed in the pathogenesis of arthropathies. Meanwhile, this review also summarized various experiments to highlight the crucial functions of selenium in maintaining the homeostasis of bone and cartilage.

源语言	英语
页（从-至）	4238-4249
页数	12
期刊	Biological Trace Element Research
卷	200
期	10
DOI	https://doi.org/10.1007/s12011-021-03022-4
出版状态	已出版 - 10月 2022

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

可持续发展目标 3 良好健康与福祉

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10.1007/s12011-021-03022-4

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引用此

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title = "Progress of Selenium Deficiency in the Pathogenesis of Arthropathies and Selenium Supplement for Their Treatment",

abstract = "Selenium, an essential trace element for human health, exerts an indispensable effect in maintaining physiological homeostasis and functions in the body. Selenium deficiency is associated with arthropathies, such as Kashin-Beck disease, rheumatoid arthritis, osteoarthritis, and osteoporosis. Selenium deficiency mainly affects the normal physiological state of bone and cartilage through oxidative stress reaction and immune reaction. This review aims to explore the role of selenium deficiency and its mechanisms existed in the pathogenesis of arthropathies. Meanwhile, this review also summarized various experiments to highlight the crucial functions of selenium in maintaining the homeostasis of bone and cartilage.",

keywords = "Arthropathies, Kashin-Beck disease, Osteoarthritis, Osteoporosis, Rheumatoid arthritis, Selenium deficiency",

author = "Huan Deng and Haobiao Liu and Zhihao Yang and Miaoye Bao and Xue Lin and Jing Han and Chengjuan Qu",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2022",

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doi = "10.1007/s12011-021-03022-4",

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TY - JOUR

T1 - Progress of Selenium Deficiency in the Pathogenesis of Arthropathies and Selenium Supplement for Their Treatment

AU - Deng, Huan

AU - Liu, Haobiao

AU - Yang, Zhihao

AU - Bao, Miaoye

AU - Lin, Xue

AU - Han, Jing

AU - Qu, Chengjuan

PY - 2022/10

Y1 - 2022/10

N2 - Selenium, an essential trace element for human health, exerts an indispensable effect in maintaining physiological homeostasis and functions in the body. Selenium deficiency is associated with arthropathies, such as Kashin-Beck disease, rheumatoid arthritis, osteoarthritis, and osteoporosis. Selenium deficiency mainly affects the normal physiological state of bone and cartilage through oxidative stress reaction and immune reaction. This review aims to explore the role of selenium deficiency and its mechanisms existed in the pathogenesis of arthropathies. Meanwhile, this review also summarized various experiments to highlight the crucial functions of selenium in maintaining the homeostasis of bone and cartilage.

AB - Selenium, an essential trace element for human health, exerts an indispensable effect in maintaining physiological homeostasis and functions in the body. Selenium deficiency is associated with arthropathies, such as Kashin-Beck disease, rheumatoid arthritis, osteoarthritis, and osteoporosis. Selenium deficiency mainly affects the normal physiological state of bone and cartilage through oxidative stress reaction and immune reaction. This review aims to explore the role of selenium deficiency and its mechanisms existed in the pathogenesis of arthropathies. Meanwhile, this review also summarized various experiments to highlight the crucial functions of selenium in maintaining the homeostasis of bone and cartilage.

KW - Arthropathies

KW - Kashin-Beck disease

KW - Osteoarthritis

KW - Osteoporosis

KW - Rheumatoid arthritis

KW - Selenium deficiency

UR - https://www.scopus.com/pages/publications/85119061363

U2 - 10.1007/s12011-021-03022-4

DO - 10.1007/s12011-021-03022-4

M3 - 文献综述

C2 - 34779998

AN - SCOPUS:85119061363

SN - 0163-4984

VL - 200

SP - 4238

EP - 4249

JO - Biological Trace Element Research

JF - Biological Trace Element Research

IS - 10

ER -

Progress of Selenium Deficiency in the Pathogenesis of Arthropathies and Selenium Supplement for Their Treatment

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