Preparation of pH-sensitive chitosan by atom transfer radical polymerization and its controlled delivery on coenzyme A

Bao Lin Guo; Jin Fang Yuan; Xiao Li Zhang; Qing Yu Gao

Preparation of pH-sensitive chitosan by atom transfer radical polymerization and its controlled delivery on coenzyme A

Bao Lin Guo
, Jin Fang Yuan
, Xiao Li Zhang
, Qing Yu Gao

Henan University
College of Henan Quality Project

科研成果: 期刊稿件 › 文章 › 同行评审

2 引用（Scopus）

摘要

A pH-sensitive chitosan material was prepared via atom transfer radical polymerization (ATRP) of chitosan with poly (ethylene glycol) methacrylate (PEGMA), which was successfully conducted in water and methanol system with CS-Br as macroinitiator and CuBr/bpy as a catalyst. The copolymer obtained was analyzed. The results of UV analysis showed that at 24 °C and under different concentrations or at 24 °C and with pH value between 3.7-9, P (CS-Br-PEGMA) can well control delivery on coenzyme A, and the release mechanism of coenzyme A was also discussed.

源语言	英语
页（从-至）	49-51
页数	3
期刊	Xiandai Huagong/Modern Chemical Industry
卷	26
期	10
出版状态	已出版 - 10月 2006
已对外发布	是

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title = "Preparation of pH-sensitive chitosan by atom transfer radical polymerization and its controlled delivery on coenzyme A",

abstract = "A pH-sensitive chitosan material was prepared via atom transfer radical polymerization (ATRP) of chitosan with poly (ethylene glycol) methacrylate (PEGMA), which was successfully conducted in water and methanol system with CS-Br as macroinitiator and CuBr/bpy as a catalyst. The copolymer obtained was analyzed. The results of UV analysis showed that at 24 °C and under different concentrations or at 24 °C and with pH value between 3.7-9, P (CS-Br-PEGMA) can well control delivery on coenzyme A, and the release mechanism of coenzyme A was also discussed.",

keywords = "Atom transfer radical polymerization (ATRP), Coenzyme A, Controlled delivery, PH-sensitivity, Polymer P (CS-Br-PEGMA)",

author = "Guo, \{Bao Lin\} and Yuan, \{Jin Fang\} and Zhang, \{Xiao Li\} and Gao, \{Qing Yu\}",

year = "2006",

month = oct,

language = "英语",

volume = "26",

pages = "49--51",

journal = "Xiandai Huagong/Modern Chemical Industry",

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TY - JOUR

T1 - Preparation of pH-sensitive chitosan by atom transfer radical polymerization and its controlled delivery on coenzyme A

AU - Guo, Bao Lin

AU - Yuan, Jin Fang

AU - Zhang, Xiao Li

AU - Gao, Qing Yu

PY - 2006/10

Y1 - 2006/10

N2 - A pH-sensitive chitosan material was prepared via atom transfer radical polymerization (ATRP) of chitosan with poly (ethylene glycol) methacrylate (PEGMA), which was successfully conducted in water and methanol system with CS-Br as macroinitiator and CuBr/bpy as a catalyst. The copolymer obtained was analyzed. The results of UV analysis showed that at 24 °C and under different concentrations or at 24 °C and with pH value between 3.7-9, P (CS-Br-PEGMA) can well control delivery on coenzyme A, and the release mechanism of coenzyme A was also discussed.

AB - A pH-sensitive chitosan material was prepared via atom transfer radical polymerization (ATRP) of chitosan with poly (ethylene glycol) methacrylate (PEGMA), which was successfully conducted in water and methanol system with CS-Br as macroinitiator and CuBr/bpy as a catalyst. The copolymer obtained was analyzed. The results of UV analysis showed that at 24 °C and under different concentrations or at 24 °C and with pH value between 3.7-9, P (CS-Br-PEGMA) can well control delivery on coenzyme A, and the release mechanism of coenzyme A was also discussed.

KW - Atom transfer radical polymerization (ATRP)

KW - Coenzyme A

KW - Controlled delivery

KW - PH-sensitivity

KW - Polymer P (CS-Br-PEGMA)

UR - https://www.scopus.com/pages/publications/33845770374

M3 - 文章

AN - SCOPUS:33845770374

SN - 0253-4320

VL - 26

SP - 49

EP - 51

JO - Xiandai Huagong/Modern Chemical Industry

JF - Xiandai Huagong/Modern Chemical Industry

IS - 10

ER -

Preparation of pH-sensitive chitosan by atom transfer radical polymerization and its controlled delivery on coenzyme A

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