Photodynamic therapy as consolidation treatment for primary cutaneous adenoid cystic carcinoma: A case report

Objective: The purpose of this case report was to evaluate the efficacy of photodynamic therapy (PDT) for a patient with primary cutaneous adenoid cystic carcinoma (PCACC). Materials and Methods: A 53-year-old female patient presented with a lesion at the pre-auricular area. After performing a local resection along a margin of 0.5 cm beyond the surrounding tissue, PCACC was clearly revealed based on the histological features and the exclusion of differentiation of other metastasis in the skin. The patient was then treated repetitively with 5-aminolevulinic acid (ALA)-PDT. After the final PDT treatment, the control pathological biopsy at the same location demonstrated no tumor cell in the specimen. Results: The 40-month follow-up diagnosis showed no evidence of recurrence or metastasis observed on the treated area. Conclusion: ALA-PDT was a safe and effective therapy for obtaining good cosmetic results and reducing recurrence in this case report.