TY - JOUR
T1 - Paper-based point-of-care immunoassays
T2 - Recent advances and emerging trends
AU - Li, Fei
AU - You, Minli
AU - Li, Shaoxiong
AU - Hu, Jie
AU - Liu, Chang
AU - Gong, Yan
AU - Yang, Huayuan
AU - Xu, Feng
N1 - Publisher Copyright:
© 2019
PY - 2020/3/1
Y1 - 2020/3/1
N2 - Immunoassay has been routinely used in hospitals and central labs. Nowadays, to further meet the requirement of widespread applications of immunoassays, it is urgently needed to produce a simplified, rapid and low-cost immunoassay to perform tests on site. To this end, paper-based point-of-care (POC) immunoassays have attracted intensive interests in recent years. In this paper, we present a comprehensive review of the recent advances and emerging trends of paper-based POC immunoassays, including the fundamental components and work principles, various detection mechanisms and applications, and existing commercialized devices/products. At last, we envision three promising development directions for paper-based POC immunoassays.
AB - Immunoassay has been routinely used in hospitals and central labs. Nowadays, to further meet the requirement of widespread applications of immunoassays, it is urgently needed to produce a simplified, rapid and low-cost immunoassay to perform tests on site. To this end, paper-based point-of-care (POC) immunoassays have attracted intensive interests in recent years. In this paper, we present a comprehensive review of the recent advances and emerging trends of paper-based POC immunoassays, including the fundamental components and work principles, various detection mechanisms and applications, and existing commercialized devices/products. At last, we envision three promising development directions for paper-based POC immunoassays.
KW - Immunoassays
KW - Lateral flow immunoassay (LFIA)
KW - Microfluidic paper-based analytical devices (μPADs)
KW - Nanoparticles
KW - Point-of-care testing (POCT)
UR - https://www.scopus.com/pages/publications/85071889022
U2 - 10.1016/j.biotechadv.2019.107442
DO - 10.1016/j.biotechadv.2019.107442
M3 - 文献综述
C2 - 31470046
AN - SCOPUS:85071889022
SN - 0734-9750
VL - 39
JO - Biotechnology Advances
JF - Biotechnology Advances
M1 - 107442
ER -