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Mechanical Characterisation and Numerical Modelling of TPMS-Based Gyroid and Diamond Ti6Al4V Scaffolds for Bone Implants: An Integrated Approach for Translational Consideration

  • Seyed Ataollah Naghavi
  • , Maryam Tamaddon
  • , Arsalan Marghoub
  • , Katherine Wang
  • , Behzad Bahrami Babamiri
  • , Kavan Hazeli
  • , Wei Xu
  • , Xin Lu
  • , Changning Sun
  • , Liqing Wang
  • , Mehran Moazen
  • , Ling Wang
  • , Dichen Li
  • , Chaozong Liu
  • University College London
  • University of Arizona
  • University of Science and Technology Beijing
  • Xi'an Jiaotong University
  • Shanghai Jiao Tong University

科研成果: 期刊稿件 › 文章 › 同行评审

124 引用 (Scopus)

摘要

Additive manufacturing has been used to develop a variety of scaffold designs for clinical and industrial applications. Mechanical properties (i.e., compression, tension, bending, and torsion response) of these scaffolds are significantly important for load-bearing orthopaedic implants. In this study, we designed and additively manufactured porous metallic biomaterials based on two different types of triply periodic minimal surface structures (i.e., gyroid and diamond) that mimic the mechanical properties of bone, such as porosity, stiffness, and strength. Physical and mechanical properties, including compressive, tensile, bending, and torsional stiffness and strength of the developed scaffolds, were then characterised experimentally and numerically using finite element method. Sheet thickness was constant at 300 μm, and the unit cell size was varied to generate different pore sizes and porosities. Gyroid scaffolds had a pore size in the range of 600–1200 μm and a porosity in the range of 54–72%, respectively. Corresponding values for the diamond were 900–1500 μm and 56–70%. Both structure types were validated experimentally, and a wide range of mechanical properties (including stiffness and yield strength) were predicted using the finite element method. The stiffness and strength of both structures are comparable to that of cortical bone, hence reducing the risks of scaffold failure. The results demonstrate that the developed scaffolds mimic the physical and mechanical properties of cortical bone and can be suitable for bone replacement and orthopaedic implants. However, an optimal design should be chosen based on specific performance requirements.

源语言英语
期刊论文编号504
期刊Bioengineering
卷9
期10
DOI
出版状态已出版 - 10月 2022

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