TY - JOUR
T1 - Inflamed dental pulp stem cells
T2 - Initial research and future development
AU - Zhao, Hua xiang
AU - Zhao, Shan mei
AU - Xin, Xin
AU - Zhang, Bo
AU - Ma, Ning hu
AU - Li, Mu jia
AU - Zhang, Meng qi
AU - Li, Ang
PY - 2014
Y1 - 2014
N2 - Background: Inflamed dental pulp stem cells are a new kind of dental pulp stem cells, and there is no systematic review on the cells by now. Objective: To systematically review the research progress in inflamed dental pulp stem cells. Methods: A computer-based online search in PubMed, Web of Science, CNKI, WanFang and VIP databases was performed for related articles published from the establishment of the databases to February 2014. The keywords were "(pulptis or inflam* dental pulp* or human dental pulp with irreversible pulpitis) and stem cell*" in English and Chinese, respectively. Hand searching was also done to obtain further information or papers about the studies. The results were qualitatively analyzed to comprehensively summarize the progress in the research of inflamed dental pulp stem cells. Results And Conclusion: Totally 11 papers were involved in result analysis that comprehensively review the research progress in inflamed dental pulp stem cells at the following aspects: the research of history, material origin, cell culture, cell-surface markers, proliferation ability, multi-directional differentiation potential, animal models and clinical use. Researches of inflamed dental pulp stem cells are still in the initial stage, and cultivating conditions and the establishment of animal models are still in the exploratory phase. Controversies still exist in the capacity of proliferation and multi-directional differentiation of the inflamed dental pulp stem cells. And fewer studies have been done in the characteristics of immunity, subpopulation and clinical use of the inflamed dental pulp stem cells.
AB - Background: Inflamed dental pulp stem cells are a new kind of dental pulp stem cells, and there is no systematic review on the cells by now. Objective: To systematically review the research progress in inflamed dental pulp stem cells. Methods: A computer-based online search in PubMed, Web of Science, CNKI, WanFang and VIP databases was performed for related articles published from the establishment of the databases to February 2014. The keywords were "(pulptis or inflam* dental pulp* or human dental pulp with irreversible pulpitis) and stem cell*" in English and Chinese, respectively. Hand searching was also done to obtain further information or papers about the studies. The results were qualitatively analyzed to comprehensively summarize the progress in the research of inflamed dental pulp stem cells. Results And Conclusion: Totally 11 papers were involved in result analysis that comprehensively review the research progress in inflamed dental pulp stem cells at the following aspects: the research of history, material origin, cell culture, cell-surface markers, proliferation ability, multi-directional differentiation potential, animal models and clinical use. Researches of inflamed dental pulp stem cells are still in the initial stage, and cultivating conditions and the establishment of animal models are still in the exploratory phase. Controversies still exist in the capacity of proliferation and multi-directional differentiation of the inflamed dental pulp stem cells. And fewer studies have been done in the characteristics of immunity, subpopulation and clinical use of the inflamed dental pulp stem cells.
KW - Dental pulp
KW - Pulpitis
KW - Review
KW - Stem cells
UR - https://www.scopus.com/pages/publications/84940319337
U2 - 10.3969/j.issn.2095-4344.2014.23.025
DO - 10.3969/j.issn.2095-4344.2014.23.025
M3 - 文章
AN - SCOPUS:84940319337
SN - 1673-8225
VL - 18
SP - 3756
EP - 3761
JO - Chinese Journal of Tissue Engineering Research
JF - Chinese Journal of Tissue Engineering Research
IS - 23
ER -