High-Entropy Layered Hydroxides: Pioneering Synthesis, Mechanistic Insights, and Multifunctional Applications in Sustainable Energy and Biomedicine

Synthesis Methodologies: We systematically investigate co-precipitation, framework-guided, and plasma-assisted hydrothermal methods for the synthesis of high-entropy layered hydroxides (HELHs), achieving precise control over the porosity, surface chemistry, and interfacial properties of ultrathin nanosheets through atomic-level mixing and defect engineering. Functional Mechanisms: HELHs possess compositional disorder, synergistic interactions among multiple components, lattice distortion-induced active sites, and inherent structural stability, collectively contributing to their superior electrochemical performance. Multifunctional Applications: HELHs excel as oxygen/hydrogen evolution reactions electrocatalysts for energy devices and enable photocatalytic reactive oxygen species generation for cancer treatment, underscoring their dual potential in sustainable energy conversion and biomedical therapeutics.