TY - GEN
T1 - Glomerular disease augments kidney accumulation of synthetic anionic polymers
AU - Prossnitz, Alexander N.
AU - Liu, Gary W.
AU - Eng, Diana G.
AU - Cheng, Yilong
AU - Pippin, Jeffrey W.
AU - Lamm, Robert J.
AU - Ngambenjawong, Chayanon
AU - Shankland, Stuart J.
AU - Pun, Suzie H.
N1 - Publisher Copyright:
© 2019 Omnipress - All rights reserved.
PY - 2019
Y1 - 2019
N2 - Statement of Purpose: Chronic kidney disease (CKD) affects over 30 million Americans. The majority of drugs that treat podocyte disease are administered systemically and have broad side effects. Since polymer-drug conjugates can alter the biodistribution and pharmokinetics of drug cargoes, we sought to elucidate the polymer properties that enhance in vivo kidney accumulation to enable new technologies to treat CKD.
AB - Statement of Purpose: Chronic kidney disease (CKD) affects over 30 million Americans. The majority of drugs that treat podocyte disease are administered systemically and have broad side effects. Since polymer-drug conjugates can alter the biodistribution and pharmokinetics of drug cargoes, we sought to elucidate the polymer properties that enhance in vivo kidney accumulation to enable new technologies to treat CKD.
UR - https://www.scopus.com/pages/publications/85065436752
U2 - 10.1016/j.biomaterials.2018.06.001
DO - 10.1016/j.biomaterials.2018.06.001
M3 - 会议稿件
AN - SCOPUS:85065436752
T3 - Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
SP - 504
BT - Society for Biomaterials Annual Meeting and Exposition 2019
PB - Society for Biomaterials
T2 - 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
Y2 - 3 April 2019 through 6 April 2019
ER -