Genetic polymorphism of Y-chromosome short tandem repeat in Elunchun ethnic group of China

Objective: To reveal the allelic frequencies and haplotype frequencies of ten Y-chromosome short tandem repeats (STR) loci (DYS392, DYS438, DYS439, DYS456, DYS459, DYS460, DYS461, DYS462, DYS389 I and DYS389 II systems) in an Elunchun population sample. Methods: PCR and polyacrylamidegel electrophoresis (PAGE) followed by silver staining were performed to analyze the blood samples from 102 unrelated E-lunchun male individuals. Results: The allele diversity values for each locus ranged from 0.418 (DYS461) to 0.727 (DYS389 I). Gene diversities were higher than 0.5 except DYS462 (0.479) and DYS461 (GATAA7.2) (0.418). Furthermore, 101 haplotypes from 10 Y-chromosome STRs loci were found in the sample and a high haplotype diversity 0.99 was determined. Conclusion: The above findings suggest that the ten Y-chromosome STR loci are valuable Y-specific markers for establishing Y-STR database, understanding human origin, paternity testing and personal identification.