TY - JOUR
T1 - Fluorenone alkaloid from caulophyllum robustum Maxim. with anti-myocardial ischemia activity
AU - Wang, Sicen
AU - Wen, Binyu
AU - Wang, Na
AU - Liu, Juntian
AU - He, Langchong
PY - 2009/4
Y1 - 2009/4
N2 - A new fluorenone alkaloid (caulophine) was isolated from the radix of Caulophyllum robustum Maxim. (collected from the Qinling mountains) using cell membrane chromatography as the screening method. Caulophine was identified as 3-(2-(dimethylamino)ethyl)-4,5-dihydroxy-1,6-dimethoxy-9H-fluoren-9-one based on physicochemic and spectroscopic analyses, particularly by NMR spectroscopic data (i.e., COSY, HMQC, HMBC, NOESY). Caulophine possessed anti-myocardial ischemia activity.
AB - A new fluorenone alkaloid (caulophine) was isolated from the radix of Caulophyllum robustum Maxim. (collected from the Qinling mountains) using cell membrane chromatography as the screening method. Caulophine was identified as 3-(2-(dimethylamino)ethyl)-4,5-dihydroxy-1,6-dimethoxy-9H-fluoren-9-one based on physicochemic and spectroscopic analyses, particularly by NMR spectroscopic data (i.e., COSY, HMQC, HMBC, NOESY). Caulophine possessed anti-myocardial ischemia activity.
KW - Anti-myocardial ischemia
KW - Caulophine
KW - Caulophyllum robustum Maxim.
UR - https://www.scopus.com/pages/publications/65549138060
U2 - 10.1007/s12272-009-1407-7
DO - 10.1007/s12272-009-1407-7
M3 - 文章
C2 - 19407969
AN - SCOPUS:65549138060
SN - 0253-6269
VL - 32
SP - 521
EP - 526
JO - Archives of Pharmacal Research
JF - Archives of Pharmacal Research
IS - 4
ER -