TY - JOUR
T1 - Electrochemical one-pot synthesis of five-membered azaheterocycles
T2 - Via [4 + 1] cyclization
AU - Wang, Qiang
AU - Wang, Xincan
AU - Liu, Qiang
AU - Xie, Guanqun
AU - Ding, Shujiang
AU - Wang, Xiaoxia
AU - Fan, Hongbo
N1 - Publisher Copyright:
© the Partner Organisations.
PY - 2020/12/7
Y1 - 2020/12/7
N2 - Various five-membered N-heterocycles, such as oxadiazoles, thiadiazoles, oxazolines and imidazoles, were prepared in one pot via electrochemical oxidation/[4 + 1] cyclization/dehydrogenative aromatization under external-oxidant-free and metal-free conditions. It is noteworthy that alcohols and electron-rich toluenes can be used as C1 synthons for the [4 + 1] cyclization together with hydrazides, N,N-dimethylhydrazinecarbothioamide, N-methylethanediamine and phenylglycinol as the four-atom fragments.
AB - Various five-membered N-heterocycles, such as oxadiazoles, thiadiazoles, oxazolines and imidazoles, were prepared in one pot via electrochemical oxidation/[4 + 1] cyclization/dehydrogenative aromatization under external-oxidant-free and metal-free conditions. It is noteworthy that alcohols and electron-rich toluenes can be used as C1 synthons for the [4 + 1] cyclization together with hydrazides, N,N-dimethylhydrazinecarbothioamide, N-methylethanediamine and phenylglycinol as the four-atom fragments.
UR - https://www.scopus.com/pages/publications/85096992421
U2 - 10.1039/d0qo01068e
DO - 10.1039/d0qo01068e
M3 - 文章
AN - SCOPUS:85096992421
SN - 2052-4110
VL - 7
SP - 3912
EP - 3917
JO - Organic Chemistry Frontiers
JF - Organic Chemistry Frontiers
IS - 23
ER -