Effect of Gusuibu on stability of moving teeth treated by surgically assisted rapid tooth movement in dogs

Objective: To investigate the effect of Gusuibu on the rapid tooth movement in dogs treated by resistance reduction and distraction osteogenesis. Methods: A total of 8 local hybrid dogs were selected in this study. The second pre-molar extracted in both sides, four posterior regions in each dog were assigned as regular tooth movement (A), rapid tooth movement (B), regular tooth movement combined with Gusuibu injection (C), rapid tooth movement combined with Gusuibu injection (D). The distance of tooth movement, pulp test and radiography examination were performed for each side on the 2nd, 3rd, 6th week. Results: The average distances of tooth movement on each side were 0.81 (A), 3.71 (B), 1.38 (C), and 3. 67 (D) mm, respectively. The distance of tooth movement in side C was significantly bigger than that in side A (P<0.05), and there was no significant difference between sides B and D. By means of X-ray examination, no significant apical root resorption was detected in each side. The stability of moving tooth in side D occurred early than side B. Conclusion: During the regular tooth movement, Gusuibu could increase the speed of tooth movement. However, during rapid tooth movement, Gusuibu could not increase the speed of tooth movement, but increase the stability of moving teeth.