Correlation Analysis of Thyroid Function and Test Results of Platelet in Patients with Acute Myocardial Infarction Undergone Percutaneous Coronary Intervention

Objective: To investigate the relationship between thyroid functions and platelet test results among acute myocardial infarction patients who received percutaneous coronary intervention therapy. Methods: A total of 122 patients between Dec 2014 and Feb 2016 hospitalized in our hospital of were enrolled in this study and divided into unstable angina (UA) and acute myocardiac infarction (AMI) groups with 45 cases and 77 cases, respectively. The basic clinical indicators were analyzed, HbA1c, blood glucose, LDL-c, HDL-c, TG, LPA, CREA, UA, hsCRP, BNP, CKMB, cTNI, and D-Dimer between the two groups were also compared. Cardiac function was evaluated by EF (%). Quartile group were adopted based on serum FT3 (nmol/L) levels. Test results of platelet such as PLT, MPV, PDW, and P-LCR, hsCRP, D-Dimer among the different FT3 groups were then compared and the relationship of MPV and FT3 in the AMI group were also analyzed. Results: The levels of hsCRP and BNP, CKMB, cTNI, and D-Dimer between UA and AMI groups had a significantly statistical difference(P<0.01). There were also significant differen in FT3 and FT4 levels(P<0.01), while TSH, TT3 and TT4 didn't show any statistical differences between these two groups (P>0.05). In the FT3 quartile groups, the lower of the FT3, the higher of MPV, hsCRP and D-Dimer. Conclusion: FT3 might be negatively related with MPV, hsCRP and D-Dimer. Low FT3 may predict the clinical risks of AMI.