Common genetic variation in MTNR1B is associated with serum testosterone, glucose tolerance, and insulin secretion in polycystic ovary syndrome patients

Lei Wang; Ying Wang; Xiaoping Zhang; Juanzi Shi; Min Wang; Zhiyun Wei; Aman Zhao; Baojie Li; Xinzhi Zhao; Qinghe Xing; Lin He

doi:10.1016/j.fertnstert.2010.01.059

Common genetic variation in MTNR1B is associated with serum testosterone, glucose tolerance, and insulin secretion in polycystic ovary syndrome patients

Lei Wang
, Ying Wang
, Xiaoping Zhang
, Juanzi Shi
, Min Wang
, Zhiyun Wei
, Aman Zhao
, Baojie Li
, Xinzhi Zhao
, Qinghe Xing
, Lin He

医学部

科研成果: 期刊稿件 › 文章 › 同行评审

19 引用（Scopus）

摘要

Melatonin plays an important role in many aspects of the human reproductive process. Our results first strongly suggest that MTNR1B mediating some functions of melatonin contributes to the phenotypic expression of polycystic ovary syndrome, which provide a new insight into the role of MTNR1B gene in the pathophysiology of the disease.

源语言	英语
页（从-至）	2486-2489.e2
期刊	Fertility and Sterility
卷	94
期	6
DOI	https://doi.org/10.1016/j.fertnstert.2010.01.059
出版状态	已出版 - 11月 2010

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可持续发展目标 3 良好健康与福祉

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10.1016/j.fertnstert.2010.01.059

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title = "Common genetic variation in MTNR1B is associated with serum testosterone, glucose tolerance, and insulin secretion in polycystic ovary syndrome patients",

abstract = "Melatonin plays an important role in many aspects of the human reproductive process. Our results first strongly suggest that MTNR1B mediating some functions of melatonin contributes to the phenotypic expression of polycystic ovary syndrome, which provide a new insight into the role of MTNR1B gene in the pathophysiology of the disease.",

author = "Lei Wang and Ying Wang and Xiaoping Zhang and Juanzi Shi and Min Wang and Zhiyun Wei and Aman Zhao and Baojie Li and Xinzhi Zhao and Qinghe Xing and Lin He",

year = "2010",

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T1 - Common genetic variation in MTNR1B is associated with serum testosterone, glucose tolerance, and insulin secretion in polycystic ovary syndrome patients

AU - Wang, Lei

AU - Wang, Ying

AU - Zhang, Xiaoping

AU - Shi, Juanzi

AU - Wang, Min

AU - Wei, Zhiyun

AU - Zhao, Aman

AU - Li, Baojie

AU - Zhao, Xinzhi

AU - Xing, Qinghe

AU - He, Lin

PY - 2010/11

Y1 - 2010/11

N2 - Melatonin plays an important role in many aspects of the human reproductive process. Our results first strongly suggest that MTNR1B mediating some functions of melatonin contributes to the phenotypic expression of polycystic ovary syndrome, which provide a new insight into the role of MTNR1B gene in the pathophysiology of the disease.

AB - Melatonin plays an important role in many aspects of the human reproductive process. Our results first strongly suggest that MTNR1B mediating some functions of melatonin contributes to the phenotypic expression of polycystic ovary syndrome, which provide a new insight into the role of MTNR1B gene in the pathophysiology of the disease.

UR - https://www.scopus.com/pages/publications/78049309374

U2 - 10.1016/j.fertnstert.2010.01.059

DO - 10.1016/j.fertnstert.2010.01.059

M3 - 文章

AN - SCOPUS:78049309374

SN - 0015-0282

VL - 94

SP - 2486-2489.e2

JO - Fertility and Sterility

JF - Fertility and Sterility

IS - 6

ER -

Common genetic variation in MTNR1B is associated with serum testosterone, glucose tolerance, and insulin secretion in polycystic ovary syndrome patients

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