Cancer Physical Hallmarks as New Targets for Improved Immunotherapy

Hui Guo; Tian Zhang; Yang Yu; Feng Xu

doi:10.1016/j.tcb.2021.03.011

Cancer Physical Hallmarks as New Targets for Improved Immunotherapy

Hui Guo
, Tian Zhang
, Yang Yu
, Feng Xu

科研成果: 期刊稿件 › 短篇评述 › 同行评审

25 引用（Scopus）

摘要

A low response rate is the major challenge for existing cancer immunotherapies. Physical cues in the tumor microenvironment (TME) have been recognized as new hallmarks of cancer, which may synergistically contribute to low immunotherapy response. Recent evidence indicates that the physical hallmarks of cancer hold great potential as new targets for improved immunotherapy.

源语言	英语
页（从-至）	520-524
页数	5
期刊	Trends in Cell Biology
卷	31
期	7
DOI	https://doi.org/10.1016/j.tcb.2021.03.011
出版状态	已出版 - 7月 2021

联合国可持续发展目标

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10.1016/j.tcb.2021.03.011

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title = "Cancer Physical Hallmarks as New Targets for Improved Immunotherapy",

abstract = "A low response rate is the major challenge for existing cancer immunotherapies. Physical cues in the tumor microenvironment (TME) have been recognized as new hallmarks of cancer, which may synergistically contribute to low immunotherapy response. Recent evidence indicates that the physical hallmarks of cancer hold great potential as new targets for improved immunotherapy.",

keywords = "cancer immunotherapy, immune-engineering, immunophenotype, mechano-nanomedicine, physical microenvironment",

author = "Hui Guo and Tian Zhang and Yang Yu and Feng Xu",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd",

year = "2021",

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doi = "10.1016/j.tcb.2021.03.011",

language = "英语",

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T1 - Cancer Physical Hallmarks as New Targets for Improved Immunotherapy

AU - Guo, Hui

AU - Zhang, Tian

AU - Yu, Yang

AU - Xu, Feng

PY - 2021/7

Y1 - 2021/7

N2 - A low response rate is the major challenge for existing cancer immunotherapies. Physical cues in the tumor microenvironment (TME) have been recognized as new hallmarks of cancer, which may synergistically contribute to low immunotherapy response. Recent evidence indicates that the physical hallmarks of cancer hold great potential as new targets for improved immunotherapy.

AB - A low response rate is the major challenge for existing cancer immunotherapies. Physical cues in the tumor microenvironment (TME) have been recognized as new hallmarks of cancer, which may synergistically contribute to low immunotherapy response. Recent evidence indicates that the physical hallmarks of cancer hold great potential as new targets for improved immunotherapy.

KW - cancer immunotherapy

KW - immune-engineering

KW - immunophenotype

KW - mechano-nanomedicine

KW - physical microenvironment

UR - https://www.scopus.com/pages/publications/85107098132

U2 - 10.1016/j.tcb.2021.03.011

DO - 10.1016/j.tcb.2021.03.011

M3 - 短篇评述

C2 - 33926772

AN - SCOPUS:85107098132

SN - 0962-8924

VL - 31

SP - 520

EP - 524

JO - Trends in Cell Biology

JF - Trends in Cell Biology

IS - 7

ER -

Cancer Physical Hallmarks as New Targets for Improved Immunotherapy

摘要

联合国可持续发展目标

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