Association between late bedtime and diabetes mellitus: A large community-based study

Study Objectives: The aim of this study was to investigate the association of bedtime with the prevalence of diabetes mellitus (DM) based on a large community-based population. Methods: In total, 5,420 participants (2,574 males and 2,846 females; aged 63.5 ± 11.0 years) from the Sleep Heart Health Study database were selected in this study. Sleep habit was recorded based on a questionnaire administered to patients upon recruitment. Bedtime was categorized as 11:00 PM and before, 11:00 PM to 12:00 AM, and 12:00 AM and later in the current study.Multivariate logistic regression was used to estimate the odds ratios (ORs) and 95%confidence intervals (CIs) to determine the relationship between bedtime and the prevalence of DM. Results: The distribution of weekday bedtime at 11:00 PM and before, 11:00 PM to 12:00 AM, 12:00 AM and later was observed in 3,316 participants (61.2%), 991 participants (18.3%), and 1,113 participants (20.5%), respectively. Meanwhile, individuals with weekday bedtime of 12:00 AM and later had a higher prevalence of DM than those with bedtime at 11:00 PM to 12:00 AM, and 11:00 PM and before (10.6%versus 5.7%versus 6.6%, respectively; P <.001). In the adjusted multivariate logistic regressionmodel, bedtime at 12:00 AM and later on a weekday was significantly associatedDMprevalence (OR 1.446, 95% CI 1.107-1.888, P =.007). No significant association was found between weekend bedtime and DM. Conclusion: Late bedtime at 12:00 AM and later on aweekday may be a risk factor for the prevalence OFDM. Stable sleep timing leads to lower risk OFDMdeserves future exploration.