TY - JOUR
T1 - Aqueous Reactive Oxygen Species Induced by He + O2 Plasmas
T2 - Chemistry Pathways and Dosage Control Approaches
AU - Chen, Chen
AU - Liu, Dingxin
AU - Yang, Aijun
AU - Chen, Hai Lan
AU - Kong, Michael G.
N1 - Publisher Copyright:
© 2017, Springer Science+Business Media, LLC.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Plasma–liquid interaction has already been a hotspot in the research field of plasma medicine. Aqueous reactive oxygen species (ROS) generated in this process are widely accepted playing a crucial role in plasma biomedical effects. In this paper, chemistry pathways among various aqueous ROS induced by He + O2 plasmas are investigated by a numerical model. Simulation results show that these aqueous ROS can be classified into two groups according to their production ways: the group of species including O, 1O2 and e directly produced in plasma, and the other group of species including O2 −, H2O2, O3, etc. produced by liquid reactions. A key reaction chain of e → O2 − → HO2(→ HO2 −) → H2O2 is found to be important in the plasma-induced liquid chemistry. Furthermore, impacts of changes in plasma and solution conditions on aqueous ROS concentrations are studied as well. It is found that changes in plasma conditions (O2 ratio in the discharge gas/power density) can globally influence the concentrations of almost every aqueous ROS, while conditions changes of the treated liquid (pH/dissolved oxygen) only partially influence the concentrations of some specific species including O2 −/HO2, O3 −/HO3 and H2O2. The revelations of the liquid chemistry pathways and the dependence of ROS dosage on the treatment conditions offer a better understanding on the plasma–liquid interactions, as well as provide optimized dosage control approaches for biomedical applications.
AB - Plasma–liquid interaction has already been a hotspot in the research field of plasma medicine. Aqueous reactive oxygen species (ROS) generated in this process are widely accepted playing a crucial role in plasma biomedical effects. In this paper, chemistry pathways among various aqueous ROS induced by He + O2 plasmas are investigated by a numerical model. Simulation results show that these aqueous ROS can be classified into two groups according to their production ways: the group of species including O, 1O2 and e directly produced in plasma, and the other group of species including O2 −, H2O2, O3, etc. produced by liquid reactions. A key reaction chain of e → O2 − → HO2(→ HO2 −) → H2O2 is found to be important in the plasma-induced liquid chemistry. Furthermore, impacts of changes in plasma and solution conditions on aqueous ROS concentrations are studied as well. It is found that changes in plasma conditions (O2 ratio in the discharge gas/power density) can globally influence the concentrations of almost every aqueous ROS, while conditions changes of the treated liquid (pH/dissolved oxygen) only partially influence the concentrations of some specific species including O2 −/HO2, O3 −/HO3 and H2O2. The revelations of the liquid chemistry pathways and the dependence of ROS dosage on the treatment conditions offer a better understanding on the plasma–liquid interactions, as well as provide optimized dosage control approaches for biomedical applications.
KW - Aqueous reactive oxygen species
KW - Chemistry pathway
KW - Cold atmospheric plasma
KW - Dosage control
KW - Plasma–liquid interaction
UR - https://www.scopus.com/pages/publications/85030866646
U2 - 10.1007/s11090-017-9854-2
DO - 10.1007/s11090-017-9854-2
M3 - 文章
AN - SCOPUS:85030866646
SN - 0272-4324
VL - 38
SP - 89
EP - 105
JO - Plasma Chemistry and Plasma Processing
JF - Plasma Chemistry and Plasma Processing
IS - 1
ER -