TY - JOUR
T1 - Analysis of the incidence of post-cholecystectomy diarrhea and its influencing factors in Hainan Province
AU - Mao, Fengjiao
AU - Zhang, Daya
AU - Huang, Xianfeng
AU - Li, Da
AU - Chen, Wenrui
AU - Zeng, Fan
AU - Chen, Chen
AU - Huang, Shimei
AU - Lv, Yanting
AU - Huang, Yuliang
AU - Chen, Runyu
AU - Mo, Ying
AU - Nie, Qiuli
AU - Zhou, Shuo
AU - Zhang, Xiaodong
AU - Yao, Qicen
AU - Du, Yiping
AU - Ran, Bo
AU - Tan, Yan
AU - Liu, Na
AU - Xie, Yunqian
AU - Bai, Feihu
N1 - Publisher Copyright:
© The Author(s) 2025.
PY - 2025/12
Y1 - 2025/12
N2 - Background and aims: Cholecystectomy is one of the most common surgical procedures for the treatment of diseases associated with gallstones, and the incidence of post-cholecystectomy diarrhea (PCD) has attracted attention in recent years. The aim of this study was to assess the prevalence of PCD in patients with gallstones and to analyze the factors influencing it. Methods: Between August 2022 and December 2024, there were 3385 cases of gallstones diagnosed by abdominal ultrasound or CT examination and laparoscopic cholecystectomy in tertiary hospitals in Hainan Province. All participants in this study were followed up by telephone within 1 year postoperatively and by telephone survey using a standardized questionnaire. The incidence of PCD was calculated, and the relevant components of the follow-up were analyzed by one-way and multifactorial logistic regression using SPSS 26.0 statistical software. Results: Four hundred seventy-nine patients (14.2%) developed PCD after undergoing laparoscopic cholecystectomy. Univariate analysis showed that age, BMI, dietary patterns, history of diabetes, alcohol consumption, gallstones and fatty liver disease were associated with the development of PCD (P < 0.05). Binary logistic regression analysis showed that age (OR = 0.532, P = 0.010), BMI (OR = 40.615, P < 0.001), dietary patterns (OR = 0.635, P = 0.013), and history of diabetes (OR = 0.263, P < 0.001) were independent risk factors. Conclusion: The incidence of PCD in Hainan Province is 14.2%. Over 50 years old, BMI, dietary pattern and history of diabetes were independent risk factors for the occurrence of PCD.
AB - Background and aims: Cholecystectomy is one of the most common surgical procedures for the treatment of diseases associated with gallstones, and the incidence of post-cholecystectomy diarrhea (PCD) has attracted attention in recent years. The aim of this study was to assess the prevalence of PCD in patients with gallstones and to analyze the factors influencing it. Methods: Between August 2022 and December 2024, there were 3385 cases of gallstones diagnosed by abdominal ultrasound or CT examination and laparoscopic cholecystectomy in tertiary hospitals in Hainan Province. All participants in this study were followed up by telephone within 1 year postoperatively and by telephone survey using a standardized questionnaire. The incidence of PCD was calculated, and the relevant components of the follow-up were analyzed by one-way and multifactorial logistic regression using SPSS 26.0 statistical software. Results: Four hundred seventy-nine patients (14.2%) developed PCD after undergoing laparoscopic cholecystectomy. Univariate analysis showed that age, BMI, dietary patterns, history of diabetes, alcohol consumption, gallstones and fatty liver disease were associated with the development of PCD (P < 0.05). Binary logistic regression analysis showed that age (OR = 0.532, P = 0.010), BMI (OR = 40.615, P < 0.001), dietary patterns (OR = 0.635, P = 0.013), and history of diabetes (OR = 0.263, P < 0.001) were independent risk factors. Conclusion: The incidence of PCD in Hainan Province is 14.2%. Over 50 years old, BMI, dietary pattern and history of diabetes were independent risk factors for the occurrence of PCD.
KW - Gallstones
KW - Laparoscopic cholecystectomy
KW - Morbidity
KW - Post-cholecystectomy diarrhea
KW - Risk factors
UR - https://www.scopus.com/pages/publications/105003003721
U2 - 10.1186/s12876-025-03810-5
DO - 10.1186/s12876-025-03810-5
M3 - 文章
C2 - 40217192
AN - SCOPUS:105003003721
SN - 1471-230X
VL - 25
JO - BMC Gastroenterology
JF - BMC Gastroenterology
IS - 1
M1 - 244
ER -
可持续发展目标 3 良好健康与福祉