Accurate and effective live bacteria microarray patterning on thick polycationic polymer layers co-patterned with HMDS

Ieong Wong; Xianting Ding; Chunsheng Wu; Chih Ming Ho

doi:10.1039/c2ra20938a

Accurate and effective live bacteria microarray patterning on thick polycationic polymer layers co-patterned with HMDS

Ieong Wong
, Xianting Ding
, Chunsheng Wu
, Chih Ming Ho

University of California at Los Angeles
Zhejiang University

科研成果: 期刊稿件 › 文章 › 同行评审

5 引用（Scopus）

摘要

A new bacteria microarray patterning technique is developed by patterning thick polycationic polymers on a glass surface, which generates high-coverage and high-precision E. coli cell patterns. Cell immobilization efficiency is greatly improved, compared to that of the conventional monolayer surface patterning approach. Cell viability tests show very low cytotoxicity of polyethyleneimine (PEI). This advancement should further accelerate biomedical and bacteriological research on the micro scale.

源语言	英语
页（从-至）	7673-7676
页数	4
期刊	RSC Advances
卷	2
期	20
DOI	https://doi.org/10.1039/c2ra20938a
出版状态	已出版 - 14 9月 2012
已对外发布	是

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abstract = "A new bacteria microarray patterning technique is developed by patterning thick polycationic polymers on a glass surface, which generates high-coverage and high-precision E. coli cell patterns. Cell immobilization efficiency is greatly improved, compared to that of the conventional monolayer surface patterning approach. Cell viability tests show very low cytotoxicity of polyethyleneimine (PEI). This advancement should further accelerate biomedical and bacteriological research on the micro scale.",

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AB - A new bacteria microarray patterning technique is developed by patterning thick polycationic polymers on a glass surface, which generates high-coverage and high-precision E. coli cell patterns. Cell immobilization efficiency is greatly improved, compared to that of the conventional monolayer surface patterning approach. Cell viability tests show very low cytotoxicity of polyethyleneimine (PEI). This advancement should further accelerate biomedical and bacteriological research on the micro scale.

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Accurate and effective live bacteria microarray patterning on thick polycationic polymer layers co-patterned with HMDS

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