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Acceleration study of a BNCT dose calculation engine based on NECP-MCX

  • Heyu Peng
  • , Qi Zheng
  • , Qingming He
  • , Tiejun Zu
  • , Yongping Wang
  • , Liangzhi Cao
  • , Hongchun Wu
  • , Sheng Wang
  • , Xiaozhi Zhang
  • The First Affiliated Hospital of Xi’an Jiaotong University
  • Xi'an Jiaotong University

科研成果: 期刊稿件文章同行评审

摘要

Boron Neutron Capture Therapy (BNCT) is an emerging cancer treatment modality where the Treatment Planning System (TPS) plays a critical role in optimizing neutron beam and boron compound dose distribution to target cancer cells while sparing healthy tissues. This paper presents the development of NECP-MCX-RT (radiation therapy), an accelerated Monte Carlo dose engine for BNCT TPS, adapted from the nuclear reactor simulation code NECP-MCX. Key innovations include a fast voxel geometry tracking algorithm that accelerates particle propagation by efficiently determining surface-crossing steps and entry directions, alongside a direct tally mechanism during transport to streamline dose calculations using voxel-specific track lengths. Additionally, a batch-based MPI parallel algorithm minimizes the inter-CPU communication overhead by deferring result summation. Validation against PHITS using a CT-based model demonstrated excellent agreement in dose distributions across tissues, with biases under 3%, while achieving a 21.91 times speedup over PHITS and an 11.97 times improvement over the original NECP-MCX in computational efficiency.

源语言英语
期刊Journal of Nuclear Science and Technology
DOI
出版状态已接受/待刊 - 2025

联合国可持续发展目标

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  1. 可持续发展目标 3 - 良好健康与福祉
    可持续发展目标 3 良好健康与福祉

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