高压电脉冲技术在肿瘤治疗领域的研究与应用进展

Based on the principle of biological effect of pulsed electric field, high-voltage electrical pulses (HVEP) technique is a new type of non-thermal local treatment, which has the characteristics of electric field-dependent, non-thermal damage and controllable range of action. The HVEP technique is currently mainly used in non-thermal food sterilization, cell electrofusion, gene transfection, electrochemotherapy, cardiac electro physiotherapy and tumor ablation. In recent years, with the deepening of basic and application research of this technology, more and more novel technologies and devices based on the HVEP are coming into clinical practice. This review summarized the research and application progress of HVEP technique in the field of tumor treatment and analyzed the future development of this technology.