聚醚醚酮的表面改性策略综述

Polyetheretherketone (PEEK) has good chemical stability and excellent mechanical properties, which is expected to be a promising choice for orthopedic, plastic and dental implants by replacing the traditional metal and ceramic materials. However, the biological inertness of the PEEK surface greatly limits the clinical transformation. Compared with mixing the active material with PEEK to improve the osseointegration ability of the material, surface modification is an effective way to improve the biological activity of peek. It can not only maintain the excellent mechanical properties of the PEEK matrix material itself, but also effectively improve the interaction between the surface of the material and the surrounding tissues. In this paper, the latest research progress of PEEK material surface modification strategies will be reviewed. Based on the principle and process of modification methods, the technical principles and research progress of PEEK materials will be summarized from three aspects, including direct physical treatment of the surface, surface physical deposition and wet chemical method, and the advantages and disadvantages of each method will be analyzed. Finally, the main challenges concerning the clinical application of modified PEEK materials are discussed and the main future direction is concluded.