经手术治疗宫颈癌患者的临床特征研究

Background: Cervical cancer is one of the malignant tumors of the reproductive tract that threaten women's health. Currently, there are different surgical treatments such as laparotomy, laparoscopy and robot assisted surgery. Previous studies have focused on the effectiveness and safety of various surgical treatments, as well as the types of human papillomavirus (HPV)infection and high-risk factors, but the clinical characteristics of patients with cervical cancer treated by surgery in this area have not been analyzed. Objective: To investigate the clinical manifestations and characteristics of patients with cervical cancer treated by surgery. Methods: The Data of 776 inpatients who were diagnosed with cervical cancer and surgically treated in the First Affiliated Hospital of Xi'an Jiaotong University from January 2013 to December 2017 were collected. To compare the clinical characteristics of the patients with different age, the place of residence and the blood type. The clinical characteristics of patients in different groups such as marriage age, gravidity, parity, menarche age, primiparity age, reasons for visiting, clinical stages and histopathological types were analyzed. Results: The average age of 776 cervical cancer patients was(59.8±9.8)years old, 64.4%(500 / 776)of them were from other cities, 88.5%(687 / 776) of them were squamous carcinoma, 7.3% (57 / 776) of them were adenocarcinoma, the rest were adenocarcinoma and other special pathological types(small cell carcinoma, neuroendocrine carcinoma, etc.). There were significant differences in the gravidity, parity, menarche age, primiparity age, reasons for visiting, clinical stages and histopathological types among patients aged ≤ 35, 36-49 and ≥ 50 years(P< 0.05), but the marriage age, differentiation of tumor cells, myometrial invasion, vascular invasion and pelvic lymph node metastasis had no statistical significance(P> 0.05). There were significant differences in the marriage age, parity, menarche age, and primiparity age among patients in this province, cities outside the province, and other provinces and cities(P< 0.05), while gravidity, reasons for visiting, clinical stage, histopathological types, differentiation degrees, myometrial invasion, vascular invasion and pelvic lymph node metastasis had no significant difference among groups(P> 0.05). There was a significant difference in gravidity among patients with different blood types(P< 0.05), and there were no significant differences in other clinical factors(P> 0.05). Conclusion: Patients with cervical cancer undergoing surgical treatment mainly suffer from squamous cell carcinoma. Most of the patients are middle-aged and elderly people from other provinces. In addition, the occurrence and development of cervical cancer is not associated with blood types and regional distribution but it is closely related to age. Therefore, the screening of cervical cancer in the elderly in this region and surrounding areas should be strengthened.