病因导向的U/P-B-C创新诊疗模式 在外科重症救治中的探索

Critical care medicine(CCM)is a multifaceted discipline challenged by the inherent heterogeneity and complexity of critical illnesses. Establishing precise, standardized diagnostic and therapeutic systems has emerged as a crucial challenge requiring urgent resolution in this field. Surgical critical care, a pivotal branch of CCM, plays an indispensable role in managing patients with severe trauma, postoperative intra-abdominal infections, solid organ transplantation, and other life-threatening conditions. Evidence-based, etiology-guided therapy serves as the cornerstone of surgical critical care, where accurate identification and timely interventions constitute vital determinants for enhancing patient survival rates and improving prognoses. This article proposes an innovative diagnostic and therapeutic paradigm termed the urgency/physics-biology-chemistry(U/P-B-C)model. Built upon the established principle of urgent(urgency, U) life support in surgical critical care, this model emphasizes a novel conceptual framework centered on etiology-based(physics-biology-chemistry, P-B-C)diagnosis and treatment. Implementing the U/P-B-C innovative diagnostic and therapeutic model in surgical critical care facilitates precise identification of the fundamental pathological mechanisms underlying critical clinical conditions with complex and dynamic clinical environments, enables systematic clarification of clinical reasoning, and ultimately supports evidence-informed decision-making. Its core objectives encompass enhancing surgical intensivists’ diagnostic the rapeutic capabilities and ensuring rigorous adherence to the principle of etiology-guided therapy, thereby providing both theoretical foundation and practical guidance for improving the success rate of patient resuscitation and optimizing prognosis in surgical critical care settings.