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持续性高过载下人脑的多孔弹性响应

  • Jin Tian
  • , Shaobao Liu
  • , Tianjian Lu
  • , Feng Xu
  • The Second Affiliated Hospital of Xi'an Jiaotong University
  • Xi'an Jiaotong University
  • Nanjing University of Aeronautics and Astronautics

科研成果: 期刊稿件文章同行评审

摘要

Sustained high overloads often acting during aerospace flights can significantly affect the passenger brain function dependent on the mechanical behavior of brain tissue and highly correlated with load characteristics. To predict the mechanical responses of human brain under sustained high overloads, the poroelastic constitutive model was adopted to characterize the mechanical behaviors of brain tissue. Built on an idealized 1D multi-layer structural model for human heads, the poroelastic control equation and the state transfer matrix for the brain tissue were derived. Through the Laplace transform and its inverse transform, the spatiotemporal distribution of the intracranial fluid pressure, the intracranial fluid seepage velocity, the brain tissue effective stress, and the brain tissue displacement were obtained. The results indicate that, the intracranial fluid infiltration has a significant impact on the responses of the brain tissue under sustained high overloads. The present work emphasizes the appropriateness and necessity of using poroelastic constitutive models to describe the mechanical behavior of brain tissue, providing important theoretical insights for the study of brain biomechanics under extreme load conditions.

投稿的翻译标题Poroelastic Responses of Human Brain Under Sustained High Overloads
源语言繁体中文
页(从-至)691-709
页数19
期刊Applied Mathematics and Mechanics
45
6
DOI
出版状态已出版 - 6月 2024

关键词

  • brain tissue mechanical response
  • poroelastic constitutive model
  • sustained high overload

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