成人低危型甲状腺微小乳头状癌临床主动监测研究进展

The incidence of papillary thyroid microcarcinoma (PTMC) increases rapidly. However, epidemio logical and autopsy studies show that the prevalence of low-risk papillary thyroid microcarcinoma (LR-PTMC) is very high, but the mortality is very low. There is over-diagnosis and over-treatment for LR-PTMC. Active sur veillance (AvS) was adopted for LR-PTMCs instead of immediate surgery, and more than 70% of the lesions re mained stable or shrank in clinical observation. Therefore, AS is recommended for LR-PTMCs in clinical guide lines of several academic organizations around the world. However, PTMC is not equal to low-risk cancer. The implementation of AS strategy requires a strict grasp of indications and full consideration of population characteris tics to ensure the maximum benefit of patients. This paper summarizes the present clinical progress of active sur veillance for adult LR-PTMC.