Visible-light-induced palladium-catalyzed formal [3 + 3] cyclization of 2-iodophenols and cyclopropenes

Yue Jie Niu; Shu Xin Gao; Xin Xin Liu; Hong Xin; Xin Hua Duan; Li Na Guo; Pin Gao; Pengfei Li

doi:10.1039/d4qo01400f

Visible-light-induced palladium-catalyzed formal [3 + 3] cyclization of 2-iodophenols and cyclopropenes

Yue Jie Niu
, Shu Xin Gao
, Xin Xin Liu
, Hong Xin
, Xin Hua Duan
, Li Na Guo
, Pin Gao
, Pengfei Li

Xi'an Jiaotong University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A visible-light-induced palladium-catalyzed formal [3 + 3] cyclization of 2-iodophenols and cyclopropenes is presented. This protocol provides a facile approach for the synthesis of 2,2-disubstituted 2H-chromenes with a quaternary carbon center in moderate to good yields. A catalytic cycle involving an aryl radical addition and an intramolecular palladium-catalyzed C-O coupling is proposed for this transformation.

Original language	English
Pages (from-to)	6194-6199
Number of pages	6
Journal	Organic Chemistry Frontiers
Volume	11
Issue number	21
DOIs	https://doi.org/10.1039/d4qo01400f
State	Published - 4 Sep 2024

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title = "Visible-light-induced palladium-catalyzed formal [3 + 3] cyclization of 2-iodophenols and cyclopropenes",

abstract = "A visible-light-induced palladium-catalyzed formal [3 + 3] cyclization of 2-iodophenols and cyclopropenes is presented. This protocol provides a facile approach for the synthesis of 2,2-disubstituted 2H-chromenes with a quaternary carbon center in moderate to good yields. A catalytic cycle involving an aryl radical addition and an intramolecular palladium-catalyzed C-O coupling is proposed for this transformation.",

author = "Niu, \{Yue Jie\} and Gao, \{Shu Xin\} and Liu, \{Xin Xin\} and Hong Xin and Duan, \{Xin Hua\} and Guo, \{Li Na\} and Pin Gao and Pengfei Li",

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year = "2024",

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doi = "10.1039/d4qo01400f",

language = "英语",

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T1 - Visible-light-induced palladium-catalyzed formal [3 + 3] cyclization of 2-iodophenols and cyclopropenes

AU - Niu, Yue Jie

AU - Gao, Shu Xin

AU - Liu, Xin Xin

AU - Xin, Hong

AU - Duan, Xin Hua

AU - Guo, Li Na

AU - Gao, Pin

AU - Li, Pengfei

PY - 2024/9/4

Y1 - 2024/9/4

N2 - A visible-light-induced palladium-catalyzed formal [3 + 3] cyclization of 2-iodophenols and cyclopropenes is presented. This protocol provides a facile approach for the synthesis of 2,2-disubstituted 2H-chromenes with a quaternary carbon center in moderate to good yields. A catalytic cycle involving an aryl radical addition and an intramolecular palladium-catalyzed C-O coupling is proposed for this transformation.

AB - A visible-light-induced palladium-catalyzed formal [3 + 3] cyclization of 2-iodophenols and cyclopropenes is presented. This protocol provides a facile approach for the synthesis of 2,2-disubstituted 2H-chromenes with a quaternary carbon center in moderate to good yields. A catalytic cycle involving an aryl radical addition and an intramolecular palladium-catalyzed C-O coupling is proposed for this transformation.

UR - https://www.scopus.com/pages/publications/85204108562

U2 - 10.1039/d4qo01400f

DO - 10.1039/d4qo01400f

M3 - 文章

AN - SCOPUS:85204108562

SN - 2052-4110

VL - 11

SP - 6194

EP - 6199

JO - Organic Chemistry Frontiers

JF - Organic Chemistry Frontiers

IS - 21

ER -

Visible-light-induced palladium-catalyzed formal [3 + 3] cyclization of 2-iodophenols and cyclopropenes

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