Abstract
A visible-light-induced palladium-catalyzed Dowd-Beckwith ring expansion/C-C bond formation cascade is described. A range of six to nine-membered β-alkenylated cyclic ketones possessing a quaternary carbon center were accessed under mild conditions. Besides styrenes, the electron-rich alkenes such as silyl enol ethers and enamides were also compatible, providing the desired β-alkylated cyclic ketones in moderate to good yields.
| Original language | English |
|---|---|
| Pages (from-to) | 1791-1795 |
| Number of pages | 5 |
| Journal | Chemical Science |
| Volume | 12 |
| Issue number | 5 |
| DOIs | |
| State | Published - 7 Feb 2021 |