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Vestibular-evoked myogenic potentials in healthy guinea pigs

  • Z. C. Chen
  • , Y. Z. Zhang
  • , Y. Z. Yang
  • , X. Y. Wei
  • , J. Hu
  • , Y. Gao
  • , F. Y. Chen
  • , H. N. Luo
  • , M. Xu
  • , Q. Zhang
  • The Second Affiliated Hospital of Xi'an Jiaotong University
  • Shangluo District People's Hospital

Research output: Contribution to journalArticlepeer-review

Abstract

Objective:To establish detection methods of air-conducted sound elicited vestibular-evoked myogenic potentials (ACS-VEMPs) in guinea pigs, including cervical vstibular-evoked myogenic potential (cVEMP) and ocular vestibular evoked myogenic potential (oVEMP). Method:Eleven healthy (250-350 g) guinea pigs (22 ears) were selected and underwent conventional ACS-cVEMP and ACS-oVEMP examinations. Parameters of waveforms were recorded. Result:The ACS-cVEMP and ACS-oVEMP could be elicited in 77.27% and 59.09% guinea pigs,respectively;threshold was (107.1±14.6)dB SPL and (115.5±15.6)dB SPL for ACS-cVEMP and ACS-oVEMP;n1,p1 latency for cVEMP was (7.4±1.5)ms and (9.3±1.6)ms,(6.4±1.4)ms and (8.1±1.8)ms for oVEMP;amlipude was (15.4±8.6)μV and (11.4±6.0)μV for cVEMP and oVEMP respectively. No statistical difference could be found in above parameters between ACS-cVEMP and ACS-oVEMP (P>0.05). Conclusion:Both ACS-cVEMP and ACS-oVEMP could be elicited in guinea pigs.

Original languageEnglish
Pages (from-to)1265-1270
Number of pages6
JournalLin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
Volume32
Issue number16
DOIs
StatePublished - 1 Aug 2018
Externally publishedYes

Keywords

  • air-conducted sound
  • guinea pigs
  • vestibular evoked myogenic potentials

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