Treatment of gastrointestinal diseases with second-generation argon plasma coagulation: An analysis of 260 cases

  • Li Zhang
  • , Lei Dong
  • , Jia Liu
  • , Jun Zhang
  • , Xiao Long Wan
  • , Jin Hai Wang

Research output: Contribution to journalArticlepeer-review

Abstract

AIM: To investigate the safety and efficacy of the second-generation argon plasma coagulation (VIO APC) for gastrointestinal diseases. METHODS: During 2007-09-14/2008-10-22, 260 patients were treated using VIO APC in a total of 289 sessions. For various indications, the new VIO APC device was used. Safety and efficacy of VIO APC were recorded after each individual treatment session. RESULTS: The mean number of treatment sessions required using VIO APC in various indications was 1.11 ± 0.31. In the palliative treatment of gastric adenocarcinoma, it was 2.50; in endoscopic hemostasis, it was 1.23; in the treatment of colorectal polypi, it was 1.15, in the treatment of upper gastrointestinal polypi, it was 1.03, in the management of self-expand stent overgrowth or tumor stenosis, it was 1.17; in the ablation of Barrett's esophagus, it was 1.13; in the ablation of gastric dysplasia, gastritis verrucosa, gastric xanthelasma and gastric or duodenal liparomphalus, only 1 session was needed. Minor complications (pain, dysphagia/odynophagia, asymptomatic gas accumulation in the intestinal wall) were observed in 10.1%-20% sessions, but no major complications (hemorrhage, perforation, stenosis) were observed. CONCLUSION: VIO APC is effective and safe for various gastrointestinal conditions. It can be widely applied to daily endoscopic treatment.

Original languageEnglish
Pages (from-to)1053-1059
Number of pages7
JournalWorld Chinese Journal of Digestology
Volume17
Issue number10
DOIs
StatePublished - 8 Apr 2009

Keywords

  • Efficacy
  • Gastrointestinal endoscopy
  • Safety
  • Second-generation argon plasma coagulation

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