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The role of epigenetic regulation in etiology of major depressive disorder

  • Xi'an Jiaotong University

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

Epigenetics refers to the heritable, but reversible, regulation of various biological functions mediated principally through changes in DNA methylation and chromatin structure derived from histone modification. Recent research indicated that epigenetic mechanisms may play vital role in etiology of major psychosis, such as schizophrenia, bipolar disorder and drug addiction. With brief introduction of epigenetic molecular mechanisms and relevance of epigenetics to human common diseases, this review focuses on epigenetic hypothesis and some supporting evidence which are recently emerged in major depressive disorder (MDD).

Original languageEnglish
Pages (from-to)665-670
Number of pages6
JournalYi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji
Volume30
Issue number6
DOIs
StatePublished - Jun 2008

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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