The pharmacokinetics, toxicology and pharmacology of oxymatrine

Pei Pei Gao; Zhen Wang; Jing Liu; Jian Gang Long

doi:10.3969/j.issn.1001-1978.2019.07.003

The pharmacokinetics, toxicology and pharmacology of oxymatrine

Pei Pei Gao
, Zhen Wang
, Jing Liu
, Jian Gang Long

Xi'an Jiaotong University

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Oxymatrine, the main active monomer composition of Sophora flavescens and Sopkoroa alopecuroides L. , has been used in clinic in China with many pharmacological effects, such as anti-inflammation, scavenging free radicals, inhibiting tumor cell proliferation and improving insulin resistance. It may have important clinical application prospects in aging related metabol-ic and cognitive degeneration. This article reviews the current research status of oxymatrine in pharmacokinetics, toxicology and pharmacology.

Original language	English
Pages (from-to)	898-902
Number of pages	5
Journal	Chinese Pharmacological Bulletin
Volume	35
Issue number	7
DOIs	https://doi.org/10.3969/j.issn.1001-1978.2019.07.003
State	Published - Jul 2019

Keywords

Cognitive function
Metabolism
Oxymatrine
Pharmacokinetics
Pharmacology
Toxicology

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10.3969/j.issn.1001-1978.2019.07.003

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abstract = "Oxymatrine, the main active monomer composition of Sophora flavescens and Sopkoroa alopecuroides L. , has been used in clinic in China with many pharmacological effects, such as anti-inflammation, scavenging free radicals, inhibiting tumor cell proliferation and improving insulin resistance. It may have important clinical application prospects in aging related metabol-ic and cognitive degeneration. This article reviews the current research status of oxymatrine in pharmacokinetics, toxicology and pharmacology.",

keywords = "Cognitive function, Metabolism, Oxymatrine, Pharmacokinetics, Pharmacology, Toxicology",

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AU - Gao, Pei Pei

AU - Wang, Zhen

AU - Liu, Jing

AU - Long, Jian Gang

PY - 2019/7

Y1 - 2019/7

N2 - Oxymatrine, the main active monomer composition of Sophora flavescens and Sopkoroa alopecuroides L. , has been used in clinic in China with many pharmacological effects, such as anti-inflammation, scavenging free radicals, inhibiting tumor cell proliferation and improving insulin resistance. It may have important clinical application prospects in aging related metabol-ic and cognitive degeneration. This article reviews the current research status of oxymatrine in pharmacokinetics, toxicology and pharmacology.

AB - Oxymatrine, the main active monomer composition of Sophora flavescens and Sopkoroa alopecuroides L. , has been used in clinic in China with many pharmacological effects, such as anti-inflammation, scavenging free radicals, inhibiting tumor cell proliferation and improving insulin resistance. It may have important clinical application prospects in aging related metabol-ic and cognitive degeneration. This article reviews the current research status of oxymatrine in pharmacokinetics, toxicology and pharmacology.

KW - Cognitive function

KW - Metabolism

KW - Oxymatrine

KW - Pharmacokinetics

KW - Pharmacology

KW - Toxicology

UR - https://www.scopus.com/pages/publications/85071313651

U2 - 10.3969/j.issn.1001-1978.2019.07.003

DO - 10.3969/j.issn.1001-1978.2019.07.003

M3 - 文章

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SN - 1001-1978

VL - 35

SP - 898

EP - 902

JO - Chinese Pharmacological Bulletin

JF - Chinese Pharmacological Bulletin

IS - 7

ER -

The pharmacokinetics, toxicology and pharmacology of oxymatrine

Abstract

Keywords

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