The Emerging Role of Gas Plasma in Oncotherapy

Xiaofeng Dai; Kateryna Bazaka; Derek J. Richard; Erik (Rik) W. Thompson; Kostya (Ken) Ostrikov

doi:10.1016/j.tibtech.2018.06.010

The Emerging Role of Gas Plasma in Oncotherapy

Xiaofeng Dai
, Kateryna Bazaka
, Derek J. Richard
, Erik (Rik) W. Thompson
, Kostya (Ken) Ostrikov

Jiangnan University
Queensland University of Technology
Translational Research Institute Australia
Department of Surgery

Research output: Contribution to journal › Review article › peer-review

120 Scopus citations

Abstract

Atmospheric pressure gas plasmas are emerging as a promising treatment in cancer that can supplement the existing set of treatment modalities and, when combined with other therapies, enhance their selectivity and efficacy against resistant cancers. With further optimisation in production and administration of plasma treatment, plasma-enabled therapy has a strong potential to mature as a tool for selectively curing highly resistant solid tumours. Although intense preclinical studies have been conducted to exploit the unique traits of plasma as an oncotherapy, few clinical studies are underway. This review identifies types of cancers and patient groups that most likely benefit from plasma oncotherapy, to introduce clinical practitioners to plasma therapy and accelerate the speed of translating plasma for cancer control in clinics.

Original language	English
Pages (from-to)	1183-1198
Number of pages	16
Journal	Trends in Biotechnology
Volume	36
Issue number	11
DOIs	https://doi.org/10.1016/j.tibtech.2018.06.010
State	Published - Nov 2018
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

chemotherapy
cold atmospheric plasma
multimodality therapy
oncotherapy
radiotherapy

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10.1016/j.tibtech.2018.06.010

Cite this

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title = "The Emerging Role of Gas Plasma in Oncotherapy",

abstract = "Atmospheric pressure gas plasmas are emerging as a promising treatment in cancer that can supplement the existing set of treatment modalities and, when combined with other therapies, enhance their selectivity and efficacy against resistant cancers. With further optimisation in production and administration of plasma treatment, plasma-enabled therapy has a strong potential to mature as a tool for selectively curing highly resistant solid tumours. Although intense preclinical studies have been conducted to exploit the unique traits of plasma as an oncotherapy, few clinical studies are underway. This review identifies types of cancers and patient groups that most likely benefit from plasma oncotherapy, to introduce clinical practitioners to plasma therapy and accelerate the speed of translating plasma for cancer control in clinics.",

keywords = "chemotherapy, cold atmospheric plasma, multimodality therapy, oncotherapy, radiotherapy",

author = "Xiaofeng Dai and Kateryna Bazaka and Richard, \{Derek J.\} and Thompson, \{Erik (Rik) W.\} and Ostrikov, \{Kostya (Ken)\}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Ltd",

year = "2018",

month = nov,

doi = "10.1016/j.tibtech.2018.06.010",

language = "英语",

volume = "36",

pages = "1183--1198",

journal = "Trends in Biotechnology",

issn = "0167-7799",

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T1 - The Emerging Role of Gas Plasma in Oncotherapy

AU - Dai, Xiaofeng

AU - Bazaka, Kateryna

AU - Richard, Derek J.

AU - Thompson, Erik (Rik) W.

AU - Ostrikov, Kostya (Ken)

PY - 2018/11

Y1 - 2018/11

N2 - Atmospheric pressure gas plasmas are emerging as a promising treatment in cancer that can supplement the existing set of treatment modalities and, when combined with other therapies, enhance their selectivity and efficacy against resistant cancers. With further optimisation in production and administration of plasma treatment, plasma-enabled therapy has a strong potential to mature as a tool for selectively curing highly resistant solid tumours. Although intense preclinical studies have been conducted to exploit the unique traits of plasma as an oncotherapy, few clinical studies are underway. This review identifies types of cancers and patient groups that most likely benefit from plasma oncotherapy, to introduce clinical practitioners to plasma therapy and accelerate the speed of translating plasma for cancer control in clinics.

AB - Atmospheric pressure gas plasmas are emerging as a promising treatment in cancer that can supplement the existing set of treatment modalities and, when combined with other therapies, enhance their selectivity and efficacy against resistant cancers. With further optimisation in production and administration of plasma treatment, plasma-enabled therapy has a strong potential to mature as a tool for selectively curing highly resistant solid tumours. Although intense preclinical studies have been conducted to exploit the unique traits of plasma as an oncotherapy, few clinical studies are underway. This review identifies types of cancers and patient groups that most likely benefit from plasma oncotherapy, to introduce clinical practitioners to plasma therapy and accelerate the speed of translating plasma for cancer control in clinics.

KW - chemotherapy

KW - cold atmospheric plasma

KW - multimodality therapy

KW - oncotherapy

KW - radiotherapy

UR - https://www.scopus.com/pages/publications/85050072993

U2 - 10.1016/j.tibtech.2018.06.010

DO - 10.1016/j.tibtech.2018.06.010

M3 - 文献综述

C2 - 30033340

AN - SCOPUS:85050072993

SN - 0167-7799

VL - 36

SP - 1183

EP - 1198

JO - Trends in Biotechnology

JF - Trends in Biotechnology

IS - 11

ER -

The Emerging Role of Gas Plasma in Oncotherapy

Abstract

UN SDGs

Keywords

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