Abstract
Stem cells with multipotent and self-renewal abilities play a vital role in regenerative medicine and tissue engineering. They can assist tissue reconstruction through specific differentiation and secretion of various bioactive macromolecules. More and more studies confirm that the cell-fate commitment can be manipulated via constructing a specific stem cell niche. The construction of specific niches with conductive materials (conducting polymers, carbon nanotubes and graphene) can promote stem cell differentiation towards electro-active lineages and emphasize the promising role of stem cells in electro-active tissue regeneration (e.g., nerve and heart). In this review, we summarize the commonly applied conductive materials for scaffold construction and evaluate their contributions in the regeneration of electro-active tissues.
| Original language | English |
|---|---|
| Pages (from-to) | 671-681 |
| Number of pages | 11 |
| Journal | Materials Science and Engineering C |
| Volume | 45 |
| DOIs | |
| State | Published - 1 Dec 2015 |
| Externally published | Yes |
Keywords
- Conductive scaffold
- Stem cell niche