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The application of antitumor drug-targeting models on liver cancer

  • Yan Yan
  • , Ningbo Chen
  • , Yunbing Wang
  • , Ke Wang
  • Xi'an Jiaotong University
  • The People’s Hospital of Sichuan Province
  • Sichuan University

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

Hepatocarcinoma animal models, such as the induced tumor model, transplanted tumor model, gene animal model, are significant experimental tools for the evaluation of targeting drug delivery system as well as the pre-clinical studies of liver cancer. The application of antitumor drug-targeting models not only furnishes similar biological characteristics to human liver cancer but also offers guarantee of pharmacokinetic indicators of the liver-targeting preparations. In this article, we have reviewed some kinds of antitumor drug-targeting models of hepatoma and speculated that the research on this field would be capable of attaining a deeper level and expecting a superior achievement in the future.

Original languageEnglish
Pages (from-to)1667-1675
Number of pages9
JournalDrug Delivery
Volume23
Issue number5
DOIs
StatePublished - 12 Jun 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Animal models
  • antitumor drugs
  • gene knock-out
  • liver cancer
  • targeting agents

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