Abstract
Hepatocarcinoma animal models, such as the induced tumor model, transplanted tumor model, gene animal model, are significant experimental tools for the evaluation of targeting drug delivery system as well as the pre-clinical studies of liver cancer. The application of antitumor drug-targeting models not only furnishes similar biological characteristics to human liver cancer but also offers guarantee of pharmacokinetic indicators of the liver-targeting preparations. In this article, we have reviewed some kinds of antitumor drug-targeting models of hepatoma and speculated that the research on this field would be capable of attaining a deeper level and expecting a superior achievement in the future.
| Original language | English |
|---|---|
| Pages (from-to) | 1667-1675 |
| Number of pages | 9 |
| Journal | Drug Delivery |
| Volume | 23 |
| Issue number | 5 |
| DOIs | |
| State | Published - 12 Jun 2016 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Animal models
- antitumor drugs
- gene knock-out
- liver cancer
- targeting agents
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