Synthesis of 2-substitued 3-aroylindenes via palladium-catalyzed carbonylative cyclization of diethyl 2-(2-(1-alkynyl)phenyl)malonates with aryl halides

Xin Hua Duan; Li Na Guo; Hai Peng Bi; Xue Yuan Liu; Yong Min Liang

doi:10.1021/ol061019v

Synthesis of 2-substitued 3-aroylindenes via palladium-catalyzed carbonylative cyclization of diethyl 2-(2-(1-alkynyl)phenyl)malonates with aryl halides

Xin Hua Duan
, Li Na Guo
, Hai Peng Bi
, Xue Yuan Liu
, Yong Min Liang

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

The palladium-catalyzed reaction of readily accessible diethyl 2-(2-(1-alkynyl)phenyl)malonates with aryl halides under a balloon pressure of CO produced 2-substitued 3-aroylindenes in good yields. The reaction is believed to proceed via cyclization of the alkyne containing a proximate nucleophilic center promoted by an acylpalladium complex.

Original language	English
Pages (from-to)	3053-3056
Number of pages	4
Journal	Organic Letters
Volume	8
Issue number	14
DOIs	https://doi.org/10.1021/ol061019v
State	Published - 6 Jul 2006
Externally published	Yes

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10.1021/ol061019v

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title = "Synthesis of 2-substitued 3-aroylindenes via palladium-catalyzed carbonylative cyclization of diethyl 2-(2-(1-alkynyl)phenyl)malonates with aryl halides",

abstract = "The palladium-catalyzed reaction of readily accessible diethyl 2-(2-(1-alkynyl)phenyl)malonates with aryl halides under a balloon pressure of CO produced 2-substitued 3-aroylindenes in good yields. The reaction is believed to proceed via cyclization of the alkyne containing a proximate nucleophilic center promoted by an acylpalladium complex.",

author = "Duan, \{Xin Hua\} and Guo, \{Li Na\} and Bi, \{Hai Peng\} and Liu, \{Xue Yuan\} and Liang, \{Yong Min\}",

year = "2006",

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day = "6",

doi = "10.1021/ol061019v",

language = "英语",

volume = "8",

pages = "3053--3056",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "14",

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T1 - Synthesis of 2-substitued 3-aroylindenes via palladium-catalyzed carbonylative cyclization of diethyl 2-(2-(1-alkynyl)phenyl)malonates with aryl halides

AU - Duan, Xin Hua

AU - Guo, Li Na

AU - Bi, Hai Peng

AU - Liu, Xue Yuan

AU - Liang, Yong Min

PY - 2006/7/6

Y1 - 2006/7/6

N2 - The palladium-catalyzed reaction of readily accessible diethyl 2-(2-(1-alkynyl)phenyl)malonates with aryl halides under a balloon pressure of CO produced 2-substitued 3-aroylindenes in good yields. The reaction is believed to proceed via cyclization of the alkyne containing a proximate nucleophilic center promoted by an acylpalladium complex.

AB - The palladium-catalyzed reaction of readily accessible diethyl 2-(2-(1-alkynyl)phenyl)malonates with aryl halides under a balloon pressure of CO produced 2-substitued 3-aroylindenes in good yields. The reaction is believed to proceed via cyclization of the alkyne containing a proximate nucleophilic center promoted by an acylpalladium complex.

UR - https://www.scopus.com/pages/publications/33746616447

U2 - 10.1021/ol061019v

DO - 10.1021/ol061019v

M3 - 文章

AN - SCOPUS:33746616447

SN - 1523-7060

VL - 8

SP - 3053

EP - 3056

JO - Organic Letters

JF - Organic Letters

IS - 14

ER -

Synthesis of 2-substitued 3-aroylindenes via palladium-catalyzed carbonylative cyclization of diethyl 2-(2-(1-alkynyl)phenyl)malonates with aryl halides

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