TY - JOUR
T1 - Synthesis and assembly strategy of electroactive biomaterials and systems for soft tissue engineering applications
AU - Yang, Dong
AU - Hu, Yi
AU - Liu, Shuai
AU - Yang, Wenhui
AU - Ren, Xi
AU - Li, Yanbing
AU - Xu, Feng
AU - Gong, Min
AU - Zhao, Yunlong
AU - Qiu, Xiaozhong
AU - Hou, Honghao
N1 - Publisher Copyright:
© 2025 Elsevier Inc.
PY - 2025/9/11
Y1 - 2025/9/11
N2 - Soft tissue injuries are a common issue affecting human health, and the extent and duration of injuries often constrain the healing process. Electroactive biomaterials have become a key medium for tissue regeneration by modulating cellular behavior, but a systematic evaluation of their potential and challenges is still limited. This review comprehensively explores electroactive biomaterials, focusing on their chemical synthesis, assembly processes, application potential, challenges faced, and future directions. First, this work elaborates on the unique and innovative features of electroactive biomaterials’ chemical synthesis and preparation techniques. Subsequently, the principles of electroactive devices and their interactions with biological tissues are described to optimize tissue repair. Finally, the application prospects of electrical stimulation technology in soft tissue engineering are explored, emphasizing its role in cell and tissue regeneration and its clinical potential. In conclusion, this review provides theoretical and practical insights into the development and application of electroactive biomaterials.
AB - Soft tissue injuries are a common issue affecting human health, and the extent and duration of injuries often constrain the healing process. Electroactive biomaterials have become a key medium for tissue regeneration by modulating cellular behavior, but a systematic evaluation of their potential and challenges is still limited. This review comprehensively explores electroactive biomaterials, focusing on their chemical synthesis, assembly processes, application potential, challenges faced, and future directions. First, this work elaborates on the unique and innovative features of electroactive biomaterials’ chemical synthesis and preparation techniques. Subsequently, the principles of electroactive devices and their interactions with biological tissues are described to optimize tissue repair. Finally, the application prospects of electrical stimulation technology in soft tissue engineering are explored, emphasizing its role in cell and tissue regeneration and its clinical potential. In conclusion, this review provides theoretical and practical insights into the development and application of electroactive biomaterials.
KW - SDG14: Life below water
KW - SDG15: Life on land
KW - SDG3: Good health and well-being
KW - bioelectrical stimulation
KW - electroactive biomaterials and systems
KW - soft tissue engineering
KW - synthesis and assembly strategy
UR - https://www.scopus.com/pages/publications/105005265253
U2 - 10.1016/j.chempr.2025.102596
DO - 10.1016/j.chempr.2025.102596
M3 - 文献综述
AN - SCOPUS:105005265253
SN - 2451-9308
VL - 11
JO - Chem
JF - Chem
IS - 9
M1 - 102596
ER -